微血管減壓術治療原發性三叉神經痛療效分析

王雄+張玉定

【摘要】 目的：探討微血管減壓術治療原發性三叉神經痛的臨床療效。方法：選取2010年1月-2013年1月本院診治的原發性三叉神經痛患者48例，按隨機數字表法分為兩組，其中通過微血管加壓術治療的23例患者為試驗組，通過射頻熱凝術治療的25例為對照組。觀察比較兩組患者的治療效果、并發癥發生情況、疼痛緩解情況、復發率及死亡率。結果：試驗組的總顯效率高于對照組，差異有統計學意義（P<0.05）；試驗組疼痛緩解情況明顯優于對照組，差異有統計學意義（P<0.05）；兩組的不良反應發生率、復發率和死亡率比較差異均無統計學意義（P>0.05）。結論：針對原發性三叉神經痛患者采用微血管減壓術可以明顯提高治療效果，減輕患者痛苦，改善患者生活質量。微血管減壓術對治療原發性三叉神經痛具有十分重要的臨床意義，值得推廣應用。

【關鍵詞】 微血管減壓術； 原發性三叉神經痛； 臨床療效

Efficacy Analysis of Micro Vascular Decompression in the Treatment of Trigeminal Neuralgia/WANG Xiong，ZHANG Yu-ding.//Medical Innovation of China，2014，11（28）：010-012

【Abstract】 Objective：To evaluate the clinical efficacy of micro vascular decompression treatment of primary trigeminal neuralgia.Method：48 patients with trigeminal neuralgia in our hospital from January 2010 to January 2013 were selected， and they were randomly divided into two groups， 23 patients were treated with micro vascular compression treatment as the experimental group， and 25 patients used radiofrequency treatment as the control group. The therapeutic effects， the occurrence of complications， pain relief， recurrence rate， mortality of the two groups were observed and compared.Result：The patients in the total efficiency of the experimental group was higher than the control group， there was significant difference （P<0.05）； pain remission in the experimental group was significantly better than the control group， the difference was statistically significant （P<0.05）； the adverse events， relapse and mortality rates of the two groups were compared， there were no significant differences （P>0.05）.Conclusion：For patients with trigeminal neuralgia micro vascular decompression surgery can significantly improve the therapeutic effect， reduce patient suffering， and improve the quality of life of patients. Micro vascular decompression surgery for the treatment of Trigeminal neuralgia has very important clinical significance， should be widely applied.

【Key words】 Micro vascular decompression； Trigeminal neuralgia； Clinical efficacy

First-authors address：Gucheng People's Hospital，Gucheng 441700，China

doi：10.3969/j.issn.1674-4985.2014.28.004

三叉神經痛是臨床常見的面部疼痛性疾病，臨床表現為三叉神經分布區域內陣發性，電擊樣劇烈疼痛[1]。三叉神經痛的致病原因包括原發性、繼發性，臨床原發性三叉神經痛較為常見。研究表明原發性三叉神經痛的發病同三叉神經的腦干區域內血管壓迫密切相關，通過解除血管壓迫，可以明顯緩解疼痛，達到治療的效果[2]。治療方案主要包括藥物治療、外科甘油注射術、射頻熱凝術、球囊壓迫術及微血管減壓術等，其中微血管減壓術治療原發性三叉神經痛具有治療效果明顯，安全性高，保留神經功能的特點，是目前臨床治療原發性三叉神經痛的首選治療方案[3]。本文通過對2010年1月-2013年1月在本院治療的48例原發性三叉神經痛患者進行分組治療，討論微血管減壓術治療原發性三叉神經痛臨床療效，現報告如下。……