小兒急性結膜炎采用兩種滴眼液方法治療的臨床效果分析

李艷艷+鄺平

【摘要】 目的：分析總結可樂必妥滴眼液與更昔洛韋滴眼液治療小兒急性結膜炎的有效性與安全性。方法：選取本院2012年4月-2014年4月收治的100例小兒急性結膜炎患者作為研究對象，按照隨機數字表法將其分為研究組和對照組各50例，研究組給予左氧氟沙星滴眼液、更昔洛韋滴眼液治療，對照組給予氧氟沙星滴眼液治療，比較兩組患兒的治療效果及不良反應發生情況。結果：研究組的治愈率70.0%和治療總有效率100%均明顯高于對照組的40.0%和76.0%，且其不良反應發生率0明顯低于對照組的12.0%，差異均有統計學意義（P<0.05）。結論：左氧氟沙星滴眼液治療小兒急性結膜炎具有更為顯著的臨床療效，且無嚴重不良反應，可于小兒急性結膜炎臨床治療中推廣應用。

【關鍵詞】 小兒； 急性結膜炎； 可樂必妥滴眼液； 更昔洛韋滴眼液； 療效

The Clinical Effect Analysis of Two Kinds of Eye Drops Method in Treatment of Children with Acute Conjunctivitis/LI Yan-yan，KUANG Ping.//Medical Innovation of China，2014，11（28）：108-110

【Abstract】 Objective：To analyze the efficacy and safety of cravit and ganciclovir ophthalmic eye drops in treatment of children with acute conjunctivitis.Method：100 pediatric patients with acute conjunctivitis from April 2012 to April 2014 treated in our hospital were selected as the research objects，they were divided into the research group and the control group according to the random number table method，50 cases in each group.The research group was treated with levofloxacin eye drops and ganciclovir ophthalmic eye drops.The control group was treated with ofloxacin eye drops.The treatment effects and adverse reactions of two groups were compared.Result：The cure rate of research group was 70.0% and total effective rate was 100%，they were significantly higher than 40.0% and 76.0% of control group，the incidence of adverse reaction of research group was 0，it was significantly lower than 12.0% of control group，the differences were statistically significant（P<0.05）.Conclusion：Levofloxacin eye drops in treatment of children with acute conjunctivitis has more remarkable clinical curative effect，and no serious adverse reactions，it is available to promote the application on the clinical treatment of children with acute conjunctivitis.

【Key words】 Children； Acute conjunctivitis； Cravit drops； Ganciclovir ophthalmic eye drops； Efficacy

First-authors address：Childrens Hospital of Jiangxi Province，Nanchang 330006，China

doi：10.3969/j.issn.1674-4985.2014.28.037

小兒急性結膜炎多由金葡菌及流感嗜血桿菌感染引起的眼部傳染性疾病，發病后患者多伴有黏液膿性分泌物及結膜充血臨床反應[1]。小兒多雙眼發病，且多發病于春秋季節，其中春季發病率尤其高。急性結膜炎患兒臨床上多伴有眼部灼熱感、異物感、刺痛感及流淚多等臨床病癥，危害較大[2]。現階段，小兒急性結膜炎臨床上多行抗生素滴眼液局部治療，常用藥物包括氧氟沙星滴眼液、諾氟沙星滴眼液等，不同藥物療效不一。本文選取本院近年來收治的100例急性結膜炎患兒作為研究對象，著重分析探討左氧氟沙星滴眼液與氧氟沙星滴眼液治療小兒急性結膜炎的臨床療效，具體分析如下。

1 資料與方法

1.1 一般資料 選取本院2012年4月-2014年4月收治的100例小兒急性結膜炎患兒作為研究對象，所有患兒臨床病癥均符合急性結膜炎臨床診斷標準[3]。……