百色市現癥高血壓各亞型患病率及其與體質糖脂和血尿酸關聯性的研究

【摘要】 目的 探討高血壓患病率，現癥高血壓單純性收縮期高血壓亞型(ISH)、單純性舒張期高血壓亞型（IDH）和聯合性高血壓亞型（SDH）的患病率及其與肥胖、血糖、血脂和血尿酸的關聯性。

方法對百色市16～81歲居民進行血壓、肥胖、血糖、血脂和血尿酸檢測，計算ISH、IDH和SDH的患病率，分析ISH、IDH和SDH與肥胖、血糖、血脂和血尿酸的關系。結果 受檢15102例，高血壓患者4427例;其中新診2605例，已診1822例;現癥3561例，ISH、IDH和SDH的患病率分別為8.7%、6.5%和8.4%，男性以SDH為主，女性以ISH為主，與非高血壓組比較，ISH組和SDH組的BMI、腰臀比、空腹血糖、血尿酸、TC、TG、LDLC和vLDLC高（P＜0.01），HDLC低（P＜0.01），IDH的BMI、腰臀比、血尿酸、TC、TG、LDLC和vLDLC高（P＜0.01），HDLC低（P＜0.01），空腹血糖差別無統計學意義（P＞0.05）；與ISH組和SDH組比較，IDH組的空腹血糖和LDLC低（P＜0.01），TG和vLDLC高（P＜0.01）。結論百色市社區(qū)居民高血壓累計患病率為29.3%，現癥患病率為23.6%，普查新發(fā)現率為12.0%，高血壓現癥患者IDH亞型患病率高于SDH和ISH；男性以IDH為主，女性以SDH為主；IDH組空腹血糖均值低于SDH組和ISH組，不高于非高血壓組，TG和vLDLC均值高于SDH組和ISH組，不同高血壓亞型臨床預防與治療方法應當分別對待，有60%的高血壓患者長期處于漏診之中，提示該地區(qū)高血壓面上防治宣傳仍然任重而道遠。

【關鍵詞】 高血壓亞型；患病率；肥胖；血糖；血脂；血尿酸

文章編號：1003-1383(2010)06-0653-04 中圖分類號：R 544.1 文獻標識碼：A

doi:10.3969/j.issn.1003-1383.2010.06.001

Analysis on morbidity rate of the new diagnosed subtypes of hypertension and the itscorrelation with glycolipid and serum uric acid in Baise

HUANG Zhaoquan，TANG Yujin，LU Kexing，LI Tianzi， PAN Xingshou， WANG Junli，

LIANG Ye， LAN Jiafu， LUGaoxiang， WANG Ruoqi，XU Xiaoping

(Cardiovascular Prevention Institute of Youjiang Medical College for

Nationality， Baise Guangxi 533000， China)

【Abstract】 ObjectiveTo study the morbidity rate of the new diagnosed subtypes of hypertension in Baise city and its relationship with metabolic syndrome (MS).

Methods The blood pressure，obesity，blood glucose，blood lipid and serum uric acid of the residents age from 16 to 81 in Baise city was measured.The indices of hypertension of isolated systolic hypertension (ISH)，isolated diastolic hypertension(IDH) and systolicdiastolic hypertension(SDH)was calculated， and their relationship with metabolic syndrome(MS) was analyzed.

Results 4427 in 15102 participants were suffered from the hypertension，2605 case were new diagnosed; 3561 present hypertensive cases，the morbidity rate of isolated systolic hypertension(ISH)，isolated diastolic hypertension(IDH) and systolic diastolic hypertension(SDH) were8.7 percent，6.5 percent and 8.4 percent respectively.SDH dominated in the male and ISH dominated in the female. Mean BMI， waist hip ratio(WHR)，mean serum urea acid， fasting blood sugar(FBS)，TC，TG，LDLC and vLDLC of SIH and SDH groups were higher than that of the control group(P＜0.01)，while the mean HDLC in SIH and SDH groups islow(P＜0.01).Mean BMI，WHR，mean serum urea acid，TC，TG，LDLC and vLDLC of IDH group were higher than that of the control group(P＜0.01)，while the mean HDLC of IDH group is lower(P＜0.01).There is no statically significant difference offasting blood sugar(FBS)between the IDH group and the control group(P＞0.05）.

Conclusion The morbidity of the new diagnosed hypertension and the subtype of IDH is higher than that of SDH and ISH groups. SDH dominated in the male and ISH dominated in the female;It featured on that mean FBS of IDH is lower than which in groups of SDH and ISH，but higher than control group，the mean of TG and vLDLC are all higher than which in groups of SDH and ISH.The prevention and treatment for different hypertension subtypes should be separated.60% hypertension patients are missed diagnosed.The propaganda of the prevention for hypertension is still remaining to be done.

【Key words】 Isolated systolic hypertension(ISH);Isolated diastolic hypertension(IDH);Systolicdiastolic hypertension(SDH);Morbidity Rate

近年來，血管事件(Vascular Event，VE)發(fā)病率呈逐年快速增長趨勢，嚴重威脅著人類的生命健康。代謝綜合征（Metabolic Syndrome，MS）是血壓、體質量和血糖異常增高，脂代謝紊亂所致，是血管事件的重要獨立危險因素，其中高血壓（PH）是核心指標，研究表明，血尿酸也是VE的獨立危險因素。按收縮壓和舒……