【摘要】 目的 觀察丙泊酚聯合應用芬太尼在無痛人流中的臨床效果。 方法將388例符合入選條件并自愿要求人工流產者隨機分為三組,A組178例,予丙泊酚+芬太尼麻醉;B組80例,予利多卡因麻醉;C組130例為對照組,不使用任何鎮痛藥物。觀察三組鎮痛效果、術中出血量以及人工流產綜合反應發生情況。 結果 三組鎮痛效果比較差異有統計學意義(P均<0.01),A組鎮痛效果最好。術中三組陰道出血量比較差異有統計學意義(P<0.05或0.01),A組出血量最多。A組人工流產綜合反應發生率為0,B組為2.5%,C組為13.9%,三組流產綜合反應發生率比較差異有統計學意義(P<0.05或0.01),A組效果最好。 結論丙泊酚聯合應用芬太尼在無痛人流術是比較安全和理想的方法,但術中需注意子宮收縮情況,備好宮縮劑,防止大出血。
【關鍵詞】 丙泊酚;芬太尼;人工流產綜合反應;鎮痛
文章編號:1003-1383(2010)06-0673-02 中圖分類號:R 719.3+4 文獻標識碼:A
doi:10.3969/j.issn.1003-1383.2010.06.009
The clinical observation of propofol combined with fentanyl intravenous anesthesiain painless artificial abortion
YANGLingling
(The Chinese Medicine Hospital of Wujiang,Wujiang 215200,Jiangsu,China)
【Abstract】 ObjectiveTo observe the clinical effect of propofol combined with fentanyl intravenous anesthesia in painless artificial abortion.
Methods 388 cases those met the inclusion criteria and voluntarily requested for abortion were randomly divided into three groups. Group A (178 cases) was given propofol and fentanyl for anesthesia,group B(80 cases)was given the lidocaine anesthesia,the control group (130 cases) wasn't given any pain medication.the analgesic effect,amount of bleeding and the incidence of abortion syndrome were observed in three groups.
Results There was significant difference of Analgesic effect and the amount of bleeding and the incidence of abortion syndrome in three groups(P<0.05 or 0.01).Group A gained the best analgesic effect and the lowest incidence rate,but the amount of bleeding was the largest.
Conclusion The propofol combined with fentanyl intravenous anesthesia in painless artificial abortion is safe and ideal method. But we should pay attention to the condition of uterine contractions,preparing for the uterotonic and preventing massive hemorrhage.
【Key words】propofol;fentanyl;abortion syndrome;analgesia
隨著生活水平的提高,人們對各種醫療操作的質量要求也越來越高。筆者對178例早孕婦女采用丙泊酚聯合芬太尼靜脈麻醉作用于無痛人工流產,取得了良好的臨床效果,現報告如下。
資料與方法
1.一般資料 選擇2008年1月~2009年6月在我院確診早孕并自愿要求人工流產且無并發癥及禁忌證者388例,年齡18~30歲,平均(23.01±3.21)歲,體重45~48 kg,平均(51.10±4.52)kg,宮內孕囊經B超證實孕齡45~60天,產次均為零。隨機分為三組,A組178例,予丙泊酚+芬太尼麻醉,B組80例,予利多卡因麻醉,C組130例,不使用任何鎮痛藥物。三組的年齡、體重、孕次、孕齡比較差異均無統計學意義(P>0.05),具有可比性。……