【摘要】 開腹手術是普外科常見的手術方式,其術后的劇烈疼痛可誘發低氧血癥、高碳酸血癥等多種并發癥,嚴重影響患者術后的生活質量。使用羅哌卡因對切口進行局部浸潤麻醉,降低了患者術后并發癥的發生率,并且操作簡單、快速、易于管理。通過對羅哌卡因切口局部浸潤麻醉用于各類開腹手術的主要進展進行歸納總結,從而討論開腹手術中羅哌卡因切口局部浸潤麻醉的可行性,在此基礎上查閱數篇近年來國內外相關研究文獻進行比對分析,對羅哌卡因切口浸潤的研究前景進行展望。
【關鍵詞】 羅哌卡因 開腹手術 局部麻醉 術后鎮痛
Research Progress of Ropivacaine Incision Infiltration in Postoperative Analgesia after Open Surgery/SUN Pengyang, LI Shenyu, AN Chengjie, ZHANG Xuezhong. //Medical Innovation of China, 2023, 20(31): -174
[Abstract] Open surgery is a common surgical method in general surgery, and the severe pain after surgery can induce various complications such as hypoxemia and hypercapnia, which seriously affects patients' postoperative quality of life. Local infiltration anesthesia of the incision with Ropivacaine reduces the incidence of postoperative complications and the operation is simple, rapid, and manageable. By summarizing the main progress of Ropivacaine local infiltration anesthesia for various types of open surgery, the feasibility of ropivacaine local infiltration anesthesia in open surgery is discussed. Based on this, several relevant domestic and foreign research literature in recent years are compared and analyzed, and the research prospects of ropivacaine incision infiltration are prospected.
[Key words] Ropivacaine Open surgery Invasive anesthesia Postoperative analgesia
First-author's address: The Second Clinical Medical College of Inner Mongolia Minzu University, Yakeshi 022150, China
doi:10.3969/j.issn.1674-4985.2023.31.039
羅哌卡因自身具有高選擇性神經阻滯的特性,因此不會有阿片類藥物相關的副作用,如手術后的過度鎮靜,腸道功能障礙。并且與布比卡因相比,羅哌卡因的安全性、感覺阻滯和鎮痛作用都更佳[1]。阿片耐受(鎮痛所需劑量增加)和阿片誘導的痛覺過敏(阿片給藥后疼痛反常增加)的患者可能導致疼痛不易控制,使得止痛、麻醉劑量進一步增加[2]。在開腹手術中的針對開放性切口使用羅哌卡因進行局部浸潤麻醉,能在術后早期提供有效鎮痛效果,從而減少患者術后的焦慮情緒,有利于患者的康復,縮短住院時間,并且還能減少非甾體抗炎藥和阿片類藥物的使用。傳統止痛藥副作用大,與傳統止痛藥相比,此鎮痛方法安全性和方便性并存,不僅增加患者的臨床滿意度,同時對今后臨床上加快術后患者康復的進程提供理論依據。……