趙琦 邱麗芹 田穎

[摘要]目的 分析乳腺癌患者的3.0T磁共振動態增強特征。方法 選取2015年1月~2019年8月我院收治的50例乳腺癌患者作為研究對象,采用磁共振成像(MRI)進行檢查,觀察患者病灶鄰近結構的改變、形態、MRI信號、強化方式和時間-信號強度曲線等指標,篩選出用于早期診斷乳腺癌的指標。結果 68%(34/50)的乳腺癌患者腫塊呈不規則形狀,32%(16/50)的乳腺癌患者腫塊呈現類圓形;80%(40/50)的患者邊緣出現“毛刺征”,侵犯Cooper韌帶(乳房懸韌帶)患者為58%(29/50),54%(27/50)的患者病灶中出現砂粒樣鈣化,44%(22/50)的患者出現局部皮膚增厚,18%(9/50)的患者乳頭發生塌陷;76%(38/50)的患者呈環行強化;26%(13/50)的患者出現對比劑的填充征,68%(34/50)的患者病灶出現快進快出型曲線,24%(12/50)的患者病灶出現平臺型曲線,8%(4/50)的患者出現緩慢上升型曲線。結論 對磁共振動態增強中各指標進行多參數的綜合評估可以作為診斷乳腺癌的重要參考因素,其有助于乳腺癌的早期診斷。
[關鍵詞]3.0 T磁共振;動態增強;乳腺癌;早期診斷
[中圖分類號] R445.2 ? ? ? ? ?[文獻標識碼] A ? ? ? ? ?[文章編號] 1674-4721(2020)9(c)-0138-03
[Abstract] Objective To analyze the 3.0T magnetic resonance dynamic enhancement characteristics of breast cancer patients. Methods A total of 50 cases of breast cancer admitted to our hospital from January 2015 to August 2019 were selected as the research subjects. Magnetic resonance imaging (MRI) was performed, the changes of adjacent structures, morphology, MRI signal, enhancement mode and time signal intensity curve were observed, indicators for early diagnosis of breast cancer were screened out. Results There were 68% (34/50) breast cancer patients with irregular shape of tumor, and 32% (16/50) breast cancer patients with round shape tumors. There were 80% (40/50) patients with "spiculation sign" on the edge, and 58% (29/50) patients with Cooper ligament (breast suspension ligament). Among the lesions, 54% (27/50) patients had sand like calcification, 44% (22/50) patients had local skin thickening, and 18% (9/50) patients with nipple collapse. 76% (38/50) patients had a circular strengthening, and 26% (13/50) patients had contrast filling signs. 68% (34/50) patients showed fast-forward and fast-out curve, 24% (12/50) patients showed plateau-shaped curve, and 8% (4/50) patients showed slowly rising curve. Conclusion Multi parameter comprehensive evaluation of various indexes in dynamic contrast-enhanced MRI can be used as an important reference factor in the diagnosis of breast cancer, which is helpful to the early diagnosis of breast cancer.
[Key words] 3.0T magnetic resonance; Dynamic enhancement; Breast cancer; Early diagnosis
目前,鉬靶X線檢查仍是診斷乳腺疾病的一種主要手段,但在某些方面,如對乳腺的成形術后、致密型的乳腺等的評價仍有較大局限性[1-2]。所以,當磁共振成像(magnetic resonance imaging,MRI)初問世時,就已經有較多的學者利用其具備的對比特點鑒別和發現各種類型的乳腺疾病,但當時的檢查結果很難令人滿意[3-4]。隨著MRI技術的日益成熟和軟硬件的不斷發展,特別是其在乳腺疾病中的檢查應用,使得乳腺影像學具有無限的前景。近年來,MRI在診斷乳腺良惡性腫瘤的敏感度和特異度已經有了較大的提高,其中,3.0T磁共振成像技術已經逐漸成為了高場MR機主流。……