王香英 李素云
【摘要】 支氣管擴張癥大多繼發于急、慢性呼吸道感染和支氣管阻塞后,反復發生支氣管炎癥,致使支氣管壁結構破壞,引起支氣管異常和持久性擴張,是呼吸系統常見病,發病率高,病程長,病理變化不可逆,反復急性加重是此病的臨床特點,該特點與患者的生活質量、致死率及預后密切相關。為進一步減少該病的急性加重次數,延緩疾病進展速度,改善患者預后及轉歸,本文通過對相關文獻資料的分析,歸納現階段對支氣管擴張癥急性加重期影響因素及預后的現代醫學研究進展,同時探究現今所存在的一些治療缺陷,以期能夠更好地指導臨床診療。
【關鍵詞】 支氣管擴張癥 預后 影響因素 研究進展
Advances in the Study of Prognostic Factors for Acute Exacerbation of Bronchiectasis/WANG Xiangying, LI Suyun. //Medical Innovation of China, 2020, 17(02): -162
[Abstract] Most of bronchiectasis disease secondary to acute and chronic respiratory infections and bronchial obstruction, recurrent bronchial inflammation, causing bronchial wall structure destruction, causing bronchial abnormalities and persistence, and it is the respiratory system diseases, high incidence, long duration, the pathological change is irreversible, and the clinical characteristics of acute exacerbation is the disease, the characteristics and the patients quality of life, death rate and prognosis are closely related. In order to further reduce the number of acute exacerbation of the disease, slow disease progression rate, improve patients prognosis and outcome, this article through the analysis of relevant literature, summarized the present stage of bronchiectasis disease influential factors and prognosis of acute aggravating period of modern medical research progress, at the same time explore some treatment defects existing in the now, in order to better guide the clinical diagnosis and treatment.
[Key words] Bronchiectasis Prognosis Factors Research progress
First-authors address: Henan University of Traditional Chinese Medicine, Zhengzhou 450000, China
doi:10.3969/j.issn.1674-4985.2020.02.041
支氣管擴張癥(簡稱支擴)具有病理變化不可逆轉,反復急性發作、死亡率高、預后差、經濟負擔重等特點,對患者的身體和心理都造成了極大的危害。因此,在早期識別患者急性加重的危險因素極其重要,筆者對相關文獻進行查閱和分析,旨在了解支氣管擴張癥急性加重的相關危險因素,以期對判斷及改善患者預后能夠有所幫助。
現代醫學研究認為,在支氣管擴張癥穩定期應積極消除其潛在病因,而最重要的是減少急性加重次數,改善臨床癥狀,延緩病情進展,提高患者的生活質量,采用科學方法篩選出可引起支氣管擴張急性加重的危險因素,從而構建合理有效的支氣管擴張癥預后風險因素評價體系,對降低急性支氣管擴張的發生率,改善患者預后具有重要意義。……