HY—D型電腦中頻藥物導入治療幼年特發性關節炎的效果

謝桂香　徐焱　劉青

[摘要]目的 觀察HY-D型電腦中頻藥物導入治療幼年特發性關節炎的效果。方法 選取2011年1月～2012年12月我院風濕免疫科收治的100例幼年特發性關節炎住院患兒作為研究對象，按隨機數字表法分成觀察組和對照組，每組50例。對照組按常規進行治療和護理，觀察組在對照組的基礎上給予HY-D型電腦中頻藥物導入治療。比較兩組患者治療前后的炎性指標水平及治療效果、恢復時間。結果 兩組患兒治療前C反應蛋白（CRP）、白介素-lβ（IL-lβ）、白介素6（IL-6）及白介素-7（IL-7）比較，差異無統計學意義（P>0.05）；觀察組患兒治療后的CRP、IL-lβ、IL-6及IL-7明顯低于對照組，差異有統計學意義（P<0.05）；觀察組ACR20、ACR50、ACR70所占比例明顯高于對照組，差異有統計學意義（P<0.05）；觀察組患兒關節腫脹消失時間、疼痛消失時間、紅細胞沉降率（ESR）恢復正常時間及住院時間均明顯短于對照組，差異有統計學意義（P<0.05）。結論 HY-D型電腦中頻藥物導入治療能有效提高幼年特發性關節炎患兒的療效，縮短恢復時間。

[關鍵詞]HY-D型電腦中頻藥物導入；幼年特發性關節炎；炎性指標；恢復時間

[中圖分類號] R445.1 [文獻標識碼] A [文章編號] 1674-4721（2018）1（a）-0154-04

[Abstract]Objective To observe the effect of HY-D type computer intermediate frequency drug introduction in the treatment of juvenile idiopathic arthritis.Methods 100 childpatients with juvenile idiopathic arthritisadmitted treated in the department of rheumatology and immunology of our hospital from January 2011 to December 2012 were selected，and divided into the observation group and the control group according to the random number table，50 cases in each group.The control group received routine treatment and nursing.The observation group was given HY-D type computer intermediate frequency drug introduction on the basis of the control group.The inflammatory indexes，treatment effect and recovery time were compared between the two groups before and after treatment.Results There were no significant differences in C-reactionprotein （CRP），interleukin-1β （IL-lβ），interleukin 6 （IL-6） and interleukin-7 （IL-7） between the two groups before treatment （P>0.05）.After treatment，the levels of CRP、IL-lβ、IL-6 and IL-7 in the observation group were significantly lower than those in the control group，the difference was statistically significant （P<0.05）.The proportion of ACR20，ACR50 and ACR70 in the observation group were obviously higher than those in the control group，the difference was statistically significant （P<0.05）.The swelling disappearance time，pain disappearance time，erythrocyte sedimentation rate （ESR），recovery time and hospitalization time of the observation group were significantly shorter than those of the control group，the difference was statistically significant （P<0.05）.Conclusion The treatment of HY-D type computerintermediate frequency drug introduction can effectively improve the effect and shorten the recovery time in children with juvenile idiopathic arthritis.

[Key words]HY-D type computer intermediate frequency drug introduction；Juvenile idiopathic arthritis；Inflammatory index；Recovery timeendprint

幼年特發性關節炎為兒童時期最常見的慢性風濕性疾病，患兒通常存在關節損傷、生長落后、殘疾及生活質量下降等關節炎表現[1]。目前，臨床對幼年特發性關節炎的治療以藥物為主，包括糖皮質激素、非甾體類消炎藥、甲氨蝶呤等，其中糖皮質激素能迅速緩解患兒的臨床癥狀，但長時間應用會給患兒帶來較多不良反應[2-3]。HY-D型電腦中頻藥物導入治療儀是一種集經皮給藥、電腦中頻和低頻于一體的藥物導入治療儀，在小兒疾病的治療和護理中均較為常用。本研究采用HY-D型電腦中頻藥物導入對幼年特發性關節炎進行治療，現報道如下。

1資料與方法

1.1 一般資料

選取2011年1月～2012年12月我院風濕免疫科收治的100例幼年特發性關節炎住院患兒作為研究對象，按隨機數字表法分成觀察組和對照組，每組各50例。觀察……