胺碘酮治療冠心病急性心肌梗死伴高危快速型心律失常的臨床研究

張愛菊

【摘要】 目的 探討冠心病急性心肌梗死伴高危快速型心律失常患者采用胺碘酮治療的臨床效果。方法 70例冠心病急性心肌梗死伴高危快速型心律失常患者作為研究對象， 隨機分為對照組和觀察組， 每組35例， 對照組采用普魯卡因胺治療， 觀察組采用胺碘酮進行治療， 比較兩組治療效果。結果 觀察組治療總有效率為94.29%， 明顯高于對照組的74.29%， 差異具有統計學意義（χ2=5.285， P=0.022<0.05）。觀察組不良反應發生率為8.57%， 明顯低于對照組的28.57%， 差異具有統計學意義（χ2=4.629， P=0.031<0.05）。結論 冠心病急性心肌梗死伴高危快速型心律失常患者采用胺碘酮治療效果顯著， 具有較高安全性， 可推廣應用。

【關鍵詞】 胺碘酮；冠心病；心肌梗死；高危快速型心律失常；效果

DOI：10.14163/j.cnki.11-5547/r.2017.23.059

Clinical research of amiodarone in the treatment of coronary heart disease acute myocardial infarction complicated with high-risk tachyarrhythmia ZHANG Ai-ju. Jilin Songyuan City Central Hospital， Songyuan 138000， China

【Abstract】 Objective To investigate clinical effect by amiodarone in the treatment of coronary heart disease acute myocardial infarction complicated with high-risk tachyarrhythmia. Methods A total of 70 coronary heart disease acute myocardial infarction complicated with high-risk tachyarrhythmia patients as study subjects were randomly divided into control group and observation group， with 35 cases in each group. The control group received procainamide for treatment， and the observation group received amiodarone for treatment. Comparison was made on curative effects between the two groups. Results The observation group had obviously higher total effective rate in treatment as 94.29% than 74.29% in the control group， and their difference had statistical significance （χ2=5.285， P=0.022<0.05）. The observation group had much lower incidence of adverse reactions as 8.57% than 28.57% in the control group， and their difference had statistical significance （χ2=4.629， P=0.031<0.05）. Conclusion Implement of amiodarone shows excellent curative effect in the treatment of coronary heart disease acute myocardial infarction complicated with high-risk tachyarrhythmia， along with high safety. This method is worth promoting and applying.

【Key words】 Amiodarone； Coronary heart disease； Myocardial infarction； High-risk tachyarrhythmia； Effectendprint