“特殊生態(tài)環(huán)境微生物及次級(jí)代謝產(chǎn)物”專輯特邀主編孫承航研究員簡(jiǎn)介

孫承航，男，1966年7月出生，中國(guó)醫(yī)學(xué)科學(xué)院&北京協(xié)和醫(yī)學(xué)院醫(yī)藥生物研究所研究員，博士研究生導(dǎo)師，微生物化學(xué)研究室主任。1999年于中國(guó)醫(yī)學(xué)科學(xué)院&中國(guó)協(xié)和醫(yī)科大學(xué)獲博士學(xué)位。以海外研究員和博士后身份，先后在日本北里研究所和約翰霍普金斯大學(xué)公共衛(wèi)生學(xué)院從事抗感染相關(guān)研究，研究領(lǐng)域：特殊生態(tài)環(huán)境藥用微生物資源勘探和新抗生素發(fā)現(xiàn)，具體包括：特殊生態(tài)環(huán)境放線菌多樣性及新穎性研究、放線菌物種鑒定、基于色譜-質(zhì)譜聯(lián)用分子網(wǎng)絡(luò)發(fā)現(xiàn)新抗生素、化合物分離純化與結(jié)構(gòu)鑒定。先后主持“十一五”和“十二五”國(guó)家科技重大專項(xiàng)、重大新藥創(chuàng)制課題“微生物產(chǎn)物化學(xué)研究”和“特境微生物創(chuàng)新藥物研究”，中國(guó)醫(yī)學(xué)科學(xué)院醫(yī)學(xué)與健康科技創(chuàng)新工程服務(wù)“一帶一路”戰(zhàn)略先導(dǎo)科研專項(xiàng)“特殊環(huán)境中藥用微生物資源發(fā)現(xiàn)與利用”，多項(xiàng)國(guó)家自然科學(xué)基金以及國(guó)際合作課題。特境來源藥用微生物資源勘探和新抗生素發(fā)現(xiàn)代表作如下(*為通訊作者)：

沙漠特境：

1.Shao-wei Liu,Norovsuren Jadambaa,Arina A.Nikandrova,Ilya A.Osterman and Cheng-hang Sun*: Exploring the Diversity and Antibacterial Potentiality of Cultivable Actinobacteria from the Soil of the Saxaul Forest in Southern Gobi Desert in Mongolia.Microorganisms 2022,10: 989.https://doi.org/10.3390/microorganisms10050989.

2.Shao-wei Liu,Ting Wang,Qin-pei Lu,Fei-na Li,Gang Wu,Zhong-ke Jiang,Xugela Habden,Lin Liu,Xiao-lin Zhang,Dmitrii A.Lukianov,Ilya A.Osterman,Petr V.Sergiev,Olga A.Dontsova and Cheng-hang Sun*:Bioprospecting of Soil-Derived Actinobacteria along the Alar-Hotan Desert Highway in the Taklamakan Desert.Frontiers in microbiology 2021,12: 604999，https://doi.org/10.3389/fmicb.2021.604999.

3.Wang Ting,Li Feina,Lu Qinpei,Habden Xugela,Razumova Elizaveta A,Osterman Ilya A,Sergiev Petr V,Dontsova Olga A,You Xuefu,Sun Chenghang*: Studies on diversity,novelty,antimicrobial activity and new antibiotics of cultivable endophytic actinobacteria isolated from psammophytes collected in Taklamakan desert.Journal of Pharmaceutical Analysis.2021,11(2): 241-250.https://doi.org/10.1016/j.jpha.2020.06.004.

紅樹林特境：

4.Qin-Pei Lu,Yong-Mei Huang,Shao-Wei Liu,Gang Wu,Qin Yang,Li-Fang Liu,Hai-Tao Zhang,Yi Qi,Ting Wang,Zhong-Ke Jiang,Jun-Jie Li,Hao Cai,Xiu-Jun Liu,Hui Luo*and Cheng-Hang Sun*: Metabolomics Tools Assisting Classic Screening Methods in Discovering New Antibiotics from Mangrove Actinomycetia in Leizhou Peninsula.Marine drugs,2021,19: 688.https://doi.org/10.3390/md19120688.

5.Qin-Pei Lu,Jing-Jing Ye,Yong-Mei Huang,Di Liu,Li-Fang Liu,Kun Dong,Elizaveta Andreevna Razumova,Ilya Andreevich Osterman,Petr Vladimirovich Sergiev,Olga Anatolievna Dontsova,Shu-Han Jia,Da-Lin Huang,Cheng-Hang Sun*: Exploitation of Potentially New Antibiotics from Mangrove Actinobacteria in Maowei Sea by Combination of Multiple Discovery Strategies.Antibiotics 2019,8(4): 36; https://doi.org/10.3390/antibiotics8040236.

6.Jiang Zhong-Ke,Tuo Li,Huang Da-Lin,Osterman Ilya A,Tyurin Anton P,Liu Shao-Wei,Lukyanov Dmitry A,Sergiev Petr V,Dontsova Olga A,Korshun Vladimir A,Li Fei-Na,Sun Cheng-Hang*: Diversity,novelty,and antimicrobial activity of endophytic actinobacteria from mangrove plants in Beilun Estuary National Nature Reserve of Guangxi,China.Frontiers in Microbiology,2018,9: 868.https://doi.org/10.3389/fmicb.2018.00868.

喀斯特洞穴特境：

7.Li Tuo,Lin Guo,Shao-Wei Liu,Jia-Meng Liu,Yu-Qin Zhang,Zhong-Ke Jiang,Xian-Fu Liu,Li Chen,Jian Zu and Cheng-Hang Sun*: Lysinibacter cavernae gen.nov.,sp.nov.,a new member of the family Microbacteriaceae isolated from a karst cave.International Journal of Systematic and Evolutionary Microbiology,2015,65: 3305-3312.https://doi.org/10.1099/ijsem.0.000415.

8.Zhong-ke Jiang,Lin Guo,Chuan Chen,Shao-wei Liu,Lin Zhang,Su-juan Dai,Qi-yang He,Xue-fu You,Xinxin Hu,Li Tuo,Wei Jiang*and Cheng-Hang Sun*: Xiakemycin A,a novel pyranonaphthoquinone antibiotic,produced by theStreptomycessp.CC8-201 from the soil of a karst cave.The Journal of Antibiotics,2015,68: 771-774.https://doi.org/10.1038/ja.2015.70.

9.Xiao-Jun Li,Su-Juan Dai,Shao-Wei Liu,Jia-Meng Liu,Li Chen,Lin Hu and Cheng-Hang Sun*:Tenggerimyces flavus sp.nov.,isolated from soil in a karst cave and emended description of the genus Tenggerimyces.International Journal of Systematic and Evolutionary Microbiology.2016,66: 1499-1505.https://doi.org/10.1099/ijsem.0.000908.

鹽湖特境：

10.Qin Yang,Pu-Yu Guo,Elena Y.Abidueva,Fei- Na Li,Chun- mei Xue,Shao- Wei Liu*,and Cheng-Hang Sun*: Hoyosella lacisalsi sp.nov.,a halotolerant actinobacterium isolated from Lake Gudzhirganskoe.Journal of Systematic and Evolutionary Microbiology.2021,71(12).https://doi.org/10.1099/ijsem.0.005145.

11.Xiao-Jun Li,Jia-Meng Liu,Yue Wu,Wei-Ming Zhang,Jing Li,Shao-Wei Liu,Gang Wu,Lin Hu,Li Chen,Da-Lin Huang,Rong-Feng Li and Cheng-Hang Sun*: Description ofSalilacibacter albusgen.nov.,sp.nov.,isolated from a dried Salt Lake and reclassification of Paraglycomyces xinjiangensis Luoet al.2015 as a later heterotypic synonym ofSalininema proteolyticumNikouet al.2015 with emended descriptions of the genusSalininemaandSalininema proteolyticum.International Journal of Systematic and Evolutionary Microbiology.2016,66: 2558-2565.https://doi.org/10.1099/ijsem.0.001093.

12.Lin Guo,Li Tuo,Xugela Habden,Yu-qin Zhang,Jia-meng Liu,Zhong-ke Jiang,Shao-wei Liu,Tohty Dilbar*and Cheng-hang Sun*: Allosalinactinospora lopnorensis gen.nov.,sp.nov.,a new member of the family Nocardiopsaceae isolated from soil.International Journal of Systematic and Evolutionary Microbiology,2015,65:206-213.https://doi.org/10.1099/ijs.0.055160-0.