How to make a better T cell: in vivo CRISPR screens have some answers
2021-01-07 23:49:09MatteoVilla
四川生理科學雜志 2021年2期
Matteo Villa
Understanding what regulates CD8+ T cell responses is key to effectively harnessing these cells in human disease. In this issue of Cell, Huang et al. and Chen et al. use in vivo CRISPR screens to discover novel regulators of CD8+ T cell immunity to engineer a more efficacious response against cancer and infections.
