葉大彬 宋文信 孫鳳



[摘要] 目的 觀察不同預后的冠心病心力衰竭患者經皮冠脈介入術(PCI)術前動態心電圖特征,分析動態心電圖特征與預后的關系。 方法 回顧性分析2018年1月—2019年1月在重慶醫科大學附屬大足醫院完成PCI治療并在術后完成1年隨訪的80例冠心病心力衰竭患者的臨床資料。所有患者均于PCI術前接受動態心電圖檢查,根據隨訪期間有無不良心血管事件發生分為預后良好組(69例)、預后不良組(11例)。比較不同預后冠心病心力衰竭患者的基線資料及術前動態心電圖特征,繪制受試者操作特征(ROC)曲線,分析術前心電圖特征,預測冠心病心力衰竭患者PCI術后不良預后的價值。 結果 冠心病心力衰竭患者不良心血管事件發生率為13.75%(11/80);預后不良組的全程全部NN間期標準差(SDNN)、24 h內每5分鐘NN間期均值的標準差(SDANN)、24 h內每5分鐘一般正常RR期間的標準差平均值(SDNNI)、全程相鄰NN間期之差的均方根值(rMSSD)值均低于預后良好組,差異有統計學意義(P < 0.05)。SDNN、SDANN、SDNNI、rMSSD預測冠心病心力衰竭患者PCI術后預后不良的曲線下面積(AUC)分別為0.865、0.920、0.848、0.918,預測價值較理想,且SDANN、rMSSD預測價值更好。結論 冠心病心力衰竭患者可通過PCI術前檢測SDNN、SDANN、SDNNI、rMSSD等心率變異性時域指標預測預后,盡早給予合理化干預,改善預后。
[關鍵詞] 冠心病;心力衰竭;經皮冠脈介入術;動態心電圖;不良心血管事件
[中圖分類號] R541.6 ? ? ? ? ?[文獻標識碼] A ? ? ? ? ?[文章編號] 1673-7210(2020)08(b)-0049-04
[Abstract] Objective To observe the characteristics of preoperative percutaneous coronary intervention (PCI) dynamic electrocardiogram characteristics in patients with coronary artery heart disease and heart failure with different prognosis and to analyze the relationship between preoperative PCI dynamic electrocardiogram and prognosis. Methods The clinical data of 80 patients with coronary artery heart disease and heart failure who were treated in Dazu Hospital Affiliated to Chongqing Medical University from January 2018 to January 2019, completed PCI treatment and one year follow-up after treatment, was retrospectively analyzed. All patients received dynamic electocardiogram detection before PCI, according to whether the patients had adverse cardiovascular events during the one year follow-up period, they were divided into good prognosis group (69 cases) and poor prognosis group (11 cases). The baseline data and preoperative dynamic electrocardiogram characteristics of patients with coronary artery heart disease and heart failure with different prognostic outcomes were compared, then the receiver operating characteristic (ROC) curve was drew to analyze the value of preoperative dynamic electrocardiogram characteristics in predicting the poor prognosis of patients with coronary artery heart disease and heart failure after PCI. Results The incidence of adverse cardiovascular events in patients with coronary artery heart disease and heart failure was 13.75% (11/80); the standard deviation of NN intervals (SDNN), standard deviation average of NN intervals (SDANN), standard deviation of normal RR intervals index (SDNNI), root mean square of successive differences (rMSSD) in the poor prognosis group were lower than those in the good prognosis group, the differences were statistically significant (P < 0.05). The ROC curve was drew to obtain SDNN, SDANN, SDNNI and rMSSD to predict the poor prognosis of patients with coronary artery heart disease and heart failure after PCI, the area under the curve (AUC) were 0.865, 0.920, 0.848 and 0.918 separately, and the predictive value was ideal. The prediction values of SDANN and rMSSD were better. Conclusion Patients with coronary artery heart disease and heart failure can predict the prognosis by SDNN, SDANN, SDNNI, rMSSD and other heart rate variability time domain indicators before PCI, to give reasonable intervention as soon as possible to improve the prognosis.
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(收稿日期:2020-05-07)