吳廣宇 顏思詩(shī) 邱君飛



[摘要] 目的 探討不同RRF狀態(tài)持續(xù)性非臥床式腹膜透析患者的臨床指標(biāo)、生活質(zhì)量及其相關(guān)因素。 方法 選取2014年7月~2016年7月我院接收的88例長(zhǎng)期腹膜透析患者,根據(jù)患者rGFR情況分成RRF組47例和無(wú)RRF組41例,記錄所有患者各項(xiàng)臨床資料以及生活質(zhì)量評(píng)分等情況,進(jìn)行分析比較。 結(jié)果 兩組患者在年齡、性別、原發(fā)病類型、體重指數(shù)、收縮壓、舒張壓、膽固醇、甘油三酯、高密度脂蛋白以及低密度脂蛋白等方面無(wú)明顯差異(P>0.05);而在冠心病例數(shù)、腹膜透析時(shí)間、血紅蛋白、血清白蛋白、血肌酐、血鉀、血鈣、血磷以及C反應(yīng)蛋白含量方面有顯著差異(P<0.05)。RRF組患者SF-36總分平均(59.50±16.82)分,顯著高于無(wú)RRF組患者的(50.84±18.73)分,兩組比較差異有統(tǒng)計(jì)學(xué)意義(P<0.05)。腹膜透析時(shí)間、血肌酐、血鈣、血鉀、血鱗及C反應(yīng)蛋白水平與腹膜透析患者生活質(zhì)量呈負(fù)相關(guān)(P<0.05);血紅蛋白、血清白蛋白水平與腹膜透析患者生活質(zhì)量呈正相關(guān)。 結(jié)論 保留RRF的持續(xù)性非臥床腹膜透析患者生活質(zhì)量更高,腹膜透析時(shí)間、營(yíng)養(yǎng)狀況、微炎癥狀態(tài)等因素與患者生活質(zhì)量具有相關(guān)性。
[關(guān)鍵詞] RRF;持續(xù)性非臥床式腹膜透析;生活質(zhì)量;相關(guān)因素
[中圖分類號(hào)] R459.5 [文獻(xiàn)標(biāo)識(shí)碼] B [文章編號(hào)] 1673-9701(2017)13-0044-04
[Abstract] Objective To investigate the clinical outcome, quality of life and its related factors in patients with persistent ambulatory peritoneal dialysis with different RRF status. Methods From July 2014 to July 2016 in our hospital 88 patients receiving long-term peritoneal dialysis patients, according to the rGFR patients were divided into RRF group (47 cases) and non RRF group(41 cases), all patients recorded the clinical data and the quality of life score, analysis and comparison. Results The age, gender, type of primary disease, body mass index, systolic blood pressure, diastolic blood pressure, cholesterol, triglyceride, high density lipoprotein, low density lipoprotein of the two groups had no significant difference(P>0.05); the reaction in coronary heart disease cases, peritoneal dialysis time, hemoglobin, serum albumin, serum creatinine, serum potassium, serum calcium, phosphorus and C reactive protein of the two groups were significant differences(P<0.05). The total score of SF-36 in the patients RRF group was(59.50±16.82) points, which was significantly higher than that in the patients without RRF, with an average of(50.84±18.73) points, and the difference between the two groups were statistically significant(P<0.05). The level of peritoneal dialysis time, serum creatinine, serum calcium, serum potassium level, phosphorus and C reactive protein and the quality of life in patients with peritoneal dialysis were negatively correlated(P<0.05); hemoglobin, serum albumin were associated with quality of life in patients with peritoneal dialysis positive relationship(P<0.05). Conclusion The quality of life of patients with continuous ambulatory peritoneal dialysis (RRF) remained high, the peritoneal dialysis time, nutritional status, micro inflammatory state and other factors were related with the quality of life.
[Key words] RRF; Persistent ambulatory peritoneal dialysis; Quality of life; Related factors
腹膜透析指的是利用人體腹膜作透析膜將透析液灌入腹膜內(nèi),同時(shí)與腹膜內(nèi)側(cè)血漿進(jìn)行物質(zhì)交換,達(dá)到清除體內(nèi)潴留水分以及代謝廢物目的的透析過(guò)程[1,2]。早期研究發(fā)現(xiàn)腹膜透析患者腹部易感染引發(fā)腹膜炎,一直以來(lái)只是作為血液透析輔助方式,對(duì)不適合做血液透析的終末期腎功能衰竭患者才考慮腹透。隨著腹膜透析技術(shù)發(fā)展,腹膜炎發(fā)病率也得到有效控制,自1979年成功進(jìn)行持續(xù)性非臥床腹膜透析后,腹透技術(shù)逐漸受到重視,也越來(lái)越多地應(yīng)用到終末期腎衰竭患者治療中[3,4]。為探究不同殘余腎功能(RRF)狀態(tài)患者臨床指標(biāo)、生活質(zhì)量情況以及相關(guān)影響因素,本研究對(duì)88例長(zhǎng)期腹膜透析患者進(jìn)行研究分析,現(xiàn)報(bào)道如下。……p>