淚道栓子治療視頻終端頑固性干眼癥的療效

周籽秀，易省平

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·臨床研究·

淚道栓子治療視頻終端頑固性干眼癥的療效

周籽秀，易省平

?METHODS:A total of 80 patients with video terminals resistant dry eyes were selected in our hospital between Mar.2013 to Mar.2015. A prospective randomized controlled study used the software SAS9.2. All the patients were randomly divided into control group and observation group, 40 patients in each group. The control group treated with drops of ophthalmic, observation group treated with lacrimal duct embolus. A course included 30d, a total of 3 courses were in the treatment. The two groups before and after treatment in patients with tear secretion test and integral-rupture time and symptoms were observed and compared.

?RESULTS: Observation group number of therapy effective and efficient eye were significantly larger than control group, and number of invalid eyes was less than that of control group, the total efficiency was higher than control group, the difference was statistically significant (P<0.05). Before treatment, the tear secretion test and tear film break-up time in two groups had no significant difference, after treatment, the above indexes of the two groups all increased, while observation group increased more significantly (P<0.05). Before treatment, scores of dry senses, foreign body sensation, visual fatigue and the total scores of symptoms in the two groups had no significant difference. After treatment, the above indexes of the two groups all decreased and the observation group decreased more significantly (P<0.05).

?CONCLUSION:Lacrimal plug has good treatment effect on the video terminal refractory dry eye, which can significantly improve the patient’s clinical symptoms, with good clinical application value.

目的：分析淚道栓子治療視頻終端頑固性干眼癥的臨床效果。

方法：選取2013-03/2015-03在我院治療的80例90眼視頻終端頑固性干眼癥患者為觀察對象，采用前瞻性隨機對照研究方法，根據軟件SAS9.2形成一組隨即數字，隨機化分為對照組和觀察組，對照組40例44眼，觀察組40例46眼。對照組給予滴眼藥治療，觀察組給予淚道栓子治療，一個療程30d，總共治療3個療程。觀察并比較兩組患者治療前后淚液分泌試驗和淚膜破裂時間以及癥狀積分。

結果：觀察組治療顯效和有效的眼數明顯多于對照組，治療無效的眼數少于對照組，觀察組治療的總有效率高于對照組，差別具有統計學意義(P<0.05)；兩組患者治療前的淚液分泌試驗和淚膜破裂時間無明顯差別，治療后兩組患者的上述指標均升高，而觀察組升高更為明顯，差別具有統計學意義(P<0.05)；治療前兩組患者的干澀感、異物感、視疲勞和癥狀總分無明顯差別，治療后兩組患者的上述指標均降低，且觀察組降低更為明顯，差別具有統計學意義(P<0.05)。

結論：淚道栓子對視頻終端頑固性干眼癥有較好的治療效果，可明顯改善患者的臨床癥狀，具有良好的臨床應用價值。

淚道栓子；視頻終端；干眼癥；臨床效果

引用：周籽秀，易省平.淚道栓子治療視頻終端頑固性干眼癥的療效.國際眼科雜志2016;16(12):2285-2287

0引言

視頻終端頑固性干眼癥是干眼癥的一種類型，也是眼科常見疾病，主要是因長時間使用終端屏幕，對眼睛、身心健康產生嚴重影響的一組疾病。視頻終端頑固性干眼癥患者的臨床病癥以眼睛干澀、紅痛、畏光、視物模糊、眼癢及對外界刺激反應敏感為主，對其生活質量造成嚴重影響[1]。臨床常給予患者滴眼藥治療，玻璃酸鈉滴眼液作為一種高分子多糖體生物材料，能夠刺激分泌大量淚液，濕潤眼球，緩解臨床病癥，但對淚液分泌試驗和淚膜破裂時間的改善效果不顯著[2-3]。……