楊 雯,廖志強
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·臨床報告·
三種方式測量中央角膜厚度的對比研究
楊 雯,廖志強
?METHODS:A total of 74 cases (148 eyes) were collected in the refractive surgery center in our hospital. The cornea thickness was measured by Germany Allegro Oculyzer; Germany Heidelberg OCT Spectralis and PachymetrySP-3000 respectively. The difference of CCT was compared usingt-test, the correlation and agreement was analyzed among the three methods with Pearson-test and Bland-Altman-test.
?Results: Mean CCT reading of Allegro Oculyzer; Heidelberg OCT Spectralis and PachymetrySP-3000 were 532.17±22.94μm, 526.53±24.52μm and 532.62±23.59μm. Thet-test showed difference between Allegro Oculyzer and Pachymetry SP-3000 (P<0.05). There was significant difference between Allegro Oculyzer and Heidelberg OCT Spectralis (P<0.05). There was no significant difference between Heidelberg OCT Spectralis and PachymetrySP-3000 (P>0.05). There was significant linear correlation among the three methods (r=0.972, 0.964, 0.973;P<0.05). There was good agreement among the three methods.
?CONCLUSION:CCT measured by Allegro Oculyzer; Heidelberg OCT Spectralis and PachymetrySP-3000 have high correlation and agreement. The three methods are complement of each other. All can be used in measurement of CCT.
目的:比較使用A型超聲角膜厚度測量計、眼前節光學相干斷層掃描儀(OCT)和Allergro Oculyzer角膜地形圖三種儀器測量中央角膜厚度的差異。
方法:選取近視治療中心就診患者74例148眼,每位患者均使用A型超聲角膜厚度測量計、眼前節光學相干斷層掃描儀和Allergro Oculyzer角膜地形圖三種儀器測量其中央角膜厚度。數據統計方式為組間兩兩比較使用配對t檢驗,組間的相關性使用Pearson相關性檢驗,組間測量方法的一致性采用Bland-altman方法。
結果:A型超聲角膜測厚、Allergro Oculyzer角膜地形圖測厚、OCT角膜測厚的平均值分別為532.17±22.94、526.53±24.52、532.62±23.59μm。三種方式組間配對t檢驗。A型超聲角膜測厚組與Allergro Oculyzer角膜地形圖測厚組比較差異有統計學意義(P<0.05)。A型超聲角膜測厚組與OCT角膜測厚組比較差異無統計學意義(P>0.05)。Allergro Oculyzer角膜地形圖測厚組與OCT角膜測厚組比較差異有統計學意義(P<0.05)。線性相關性統計分析顯示A型超聲角膜測厚組、Allergro Oculyzer角膜地形圖測厚組、OCT角膜測厚組兩兩呈正相關(r=0.972、0.964、0.973,P<0.05)。三種方式測量角膜厚度的一致性分析為具有較好的一致性。
結論:A型超聲角膜測厚、Allergro Oculyzer角膜地形圖測厚、OCT角膜測厚三種測量方式對于CCT的測量具有明顯的相關性和較好的一致性,臨床上三種測量方式可以互為補充,相互參考。
中央角膜厚度;鷹視眼前節分析診斷系統;海德堡光學相干斷層眼前節掃描儀; A型超聲
引用:楊雯,廖志強.三種方式測量中央角膜厚度的對比研究.國際眼科雜志2016;16(12):2305-2307
角膜中央厚度不僅對于眼科的臨床診斷,而且對于眼科的治療都是一項重要的參數指標,現在越來越受到廣大眼科醫師的重視。特別是屈光手術前中央角膜厚度的測量更是關系到能否實施屈光手術以及采用何種手術方式進行手術,對于屈光術后安全性的判定也是必不可少的[1-2]。……