米索前列醇聯合鈣劑應用于預防與治療產后出血

【摘要】:目的:研究口服米索前列醇防治產后出血的可行性，有效性和安全性。方法:在我院內選擇正常月妊娠陰道分娩者100例，將其完全隨機分為兩組，每組研究50例，研究組在胎盤娩出后口服國產米索前列醇600μg;對照則在胎盤娩出后宮體注射縮宮素20iu，觀察產后2h內的出血量及產后出血發生率。結果:產后2h內的出血量及產后出血發生率，研究組均較對照組要低，進行統計學分析，差異有顯著地意義(p<0.05)。結論:口服米索前列醇防治產后出血是一種安全、有效的方法且效果優于縮宮素。如果聯合鈣劑應用于產后出血效果則更為突出。

【關鍵詞】:米索前列醇;鈣劑;產后出血;縮宮素;預防

【中圖分類號】R714.46+1【文獻標識碼】A【文章編號】1007-8517(2010)08-014-2

[Abstract]:Objective:To study the curative effect and the feasibility of the treatment of postpartum haemorrhage with misoprostol. Method:choice in my hospital on a normal vaginal delivery were 100 cases of pregnancy，will it completely randomly divided into two groups，each group studied 50 cases，the Study Group made in the placenta after the oral administration of misoprostol 600μg;control body in the placenta Temple injection of oxytocin 20iu，observed within 2h post-partum bleeding volume and the incidence of postpartum hemorrhage. Results:within 2h post-partum bleeding volume and the incidence of postpartum hemorrhage study group was lower than those in the control group carried out statistical analysis，the difference was significantly significant(p<0.05). Conclusions:Prevention of postpartum hemorrhage of oral misoprostol is a safe and effective method and more effective than oxytocin. If the joint effects of calcium applied to post-partum haemorrhage was more prominent.

[key words]:Misoprostol;calcium;oxytocin;prevent;postpartum hemorrhage