促甲狀腺激素檢測在孕前優生健康檢查中的應用價值

柏愛芳

【摘要】目的：分析孕前優生健康檢查中促甲狀腺激素檢測的應用價值。方法：選取2021年9月—2022年9月于我院開展孕前優生健康檢查的80例計劃妊娠女性為研究對象，所有受檢者均開展促甲狀腺激素檢測并詳細記錄結果，以促甲狀腺激素異常率及妊娠結局展開分析。結果：80例計劃妊娠女性孕前優生健康檢查中，甲狀腺功能正常者69例，檢出率86.25%；甲狀腺功能異常者11例，檢出率13.75%，其中亞甲減患者9例，占比為11.25%，甲狀腺功能亢進患者2例，占比為2.50%。甲狀腺功能正常者不良妊娠結局發生率為0.00%，低于甲狀腺功能異常者的27.27%，有顯著差異（P<0.05）。結論：孕前優生健康檢查中促甲狀腺激素檢測的應用能夠準確判定受檢者的甲狀腺功能狀況，預防生育風險事件的發生，減少臨床不良妊娠結局，有臨床推廣意義。

【關鍵詞】促甲狀腺激素；孕前；健康檢查；妊娠結局

The application value of thyroid-stimulating hormone detection in pre-pregnancy eugenics health examination

BAI Aifang

Maternal and Child Health Care Center of Yandu District， Yancheng City， Yancheng， Jiangsu 224000， China

【Abstract】Objective：To analyze the application value of thyroid-stimulating hormone detection in pre-pregnancy eugenics health examination.Methods：80 planned pregnant women who underwent pre-pregnancy eugenics health examination in our hospital from September 2021 to September 2022 were selected as the research subjects.All subjects underwent thyroid stimulating hormone test and the results were recorded in detail，and the rate of thyroid stimulating hormone abnormality and pregnancy outcome were analyzed. Results：Among the 80 planned pregnant women who underwent re-pregnancy eugenics health examination，69 cases had normal thyroid function，with a detection rate of 86.25%；There were 11 cases with abnormal thyroid function，with a detection rate of 13.75%，among them，9 cases with subclinical hypothyroidism，accounting for 11.25%，and 2 cases with hyperthyroidism，accounting for 2.50%.The incidence of adverse pregnancy outcomes in patients with normal thyroid function was 0.00%，which was lower than 27.27% in patients with abnormal thyroid function，with a significant difference （P<0.05）.Conclusion：The application of thyroid stimulating hormone detection in pre pregnancy eugenics health examination can accurately determine the thyroid function status of the tested person，prevent the occurrence of fertility risk events，reduce clinical adverse pregnancy outcomes，and have clinical promotion significance.

【Key Words】Thyroid stimulating hormone； Before pregnancy； Health examination； Pregnancy outcome

受到日常生活環境污染、電磁輻射、不良飲食狀況、遺傳等諸多因素影響，我國新生兒缺陷的問題較為嚴重，這些有缺陷的新生兒不僅使其家庭承受沉重負擔，同時也給社會帶來了巨大壓力。基于此，計劃妊娠的夫婦可通過方便且科學的孕前優生健康等醫學手段展開檢查。實施孕前優生健康檢查其主要目的為防止胎兒發生缺陷，減少妊娠不良結局，對于人口素質提升具有重要意義，可有效貫徹優生優育的政策[1]。孕前優生健康檢查項目主要涉及血尿常規、肝腎功能、乙肝5項、梅毒、血糖、促甲狀腺激素、病毒篩查（風疹病毒、巨細胞病毒、弓形體）、體格檢查、婦科超聲、陰道分泌物等。其中促甲狀腺激素檢查作為孕前優生健康檢查重要的項目之一，隨著甲狀腺疾病發生率不斷上升，促甲狀腺激素檢查對于保障妊娠結局起到了不可忽視的作用[2]。……