上海市某療養(yǎng)院體檢人群體重指數(shù)與血脂水平及非酒精性脂肪肝關(guān)系的調(diào)查研究

吳玉梅

[摘要] 目的 探討某療養(yǎng)院體檢人群體重指數(shù)與血脂水平及非酒精性脂肪肝關(guān)系。 方法 選擇我院進(jìn)行體檢的人群共10245例為研究對象，根據(jù)BMI結(jié)果分為<18.5 kg/m2組（A組）179例，18.5～23.9 kg/m2組（B組）3923例，24.0～27.9 kg/m2組（C組）4650例，≥28.0 kg/m2組（D組）1493例，比較不同BMI分組者高TG血癥、高TC血癥、混合型高脂血癥以及非酒精性脂肪肝發(fā)生率。 結(jié)果 不同BMI分組TC、TG、HDL-C、LDL-C水平比較，差異有統(tǒng)計學(xué)意義（P<0.01）；其中B組、C組及D組TC、TG、LDL-C水平顯著高于A組，C組、D組TC、TG、LDL-C水平顯著高于B組，D組TC、TG、LDL-C水平顯著高于C組，差異均有統(tǒng)計學(xué)意義（P<0.01）；B組、C組及D組HDL-C顯著低于A組，C組、D組HDL-C水平顯著低于B組，D組HDL-C顯著低于C組，差異均有統(tǒng)計學(xué)意義（P<0.01）。不同BMI分組者高TC血癥、高TG血癥、混合型高脂血癥、非酒精性脂肪肝發(fā)生率比較，差異有統(tǒng)計學(xué)意義（P<0.01）；不同BMI分組者高TC血癥、高TG血癥、混合型高脂血癥、非酒精性脂肪肝發(fā)生率比較，差異有統(tǒng)計學(xué)意義（P<0.01）；其中D組發(fā)病率最高，其次為C組、B組，A組發(fā)病率最低。 結(jié)論 健康體檢人群體重指數(shù)越高，高脂血癥、非酒精性脂肪肝發(fā)生率越高。

[關(guān)鍵詞] 健康體檢人群；體重指數(shù)；血脂水平；非酒精性脂肪肝

[中圖分類號] R575.5 [文獻(xiàn)標(biāo)識碼] B [文章編號] 1673-9701（2017）30-0121-03

[Abstract] Objective To investigate the relationship between body mass index and blood lipid level， nonalcoholic fatty liver of physical examination population in a sanatorium. Methods A total of 10245 patients who underwent physical examination in our hospital were selected as the study subjects. According to the BMI results， the patients were divided into <18.5 kg/m2 group （group A， n=179）， 18.5-23.9 kg/m2 group （group B， n=3923）， 24.0-27.9 kg/m2 group （group C， n=4650） and ≥28.0 kg/m2 group（group D， n=1493）. The incidence rates of hyperglycemia， hyperlipidemia， mixed hyperlipidemia and nonalcoholic fatty liver disease among different BMI groups were compared. Results There were significant differences in the levels of TC， TG， HDL-C and LDL-C in different BMI groups（P<0.01）. The levels of TC， TG and LDL-C in group B， group C and group D were significantly higher than those in group A. The levels of TC， TG and LDL-C in group C and group D were significantly higher than those in the group A， and the levels of TC， TG and LDL-C in group D were significantly higher than those in the group C. And the difference was significant （P<0.01）. The HDL-C in group B， group C and group D was significantly lower than that in group A， and the HDL-C of group C and group D was significantly lower than that in group B， and the HDL-C in group D was significantly lower than that in group C. The difference was statistically significant（P<0.01）. There were significant differences in the incidences of hyperlipidemia， hyperglycemia， mixed hyperlipidemia and nonalcoholic fatty liver disease in different BMI groups（P<0.01）. The incidence of D group was the highest， followed by group C， group B， and group A had the lowest incidence. Conclusion The higher the body mass index of the healthy physical examination population， the higher the incidence of hyperlipidemia and nonalcoholic fatty liver disease.endprint