朱艷萍 趙霞 毛善林 武青
【摘要】 目的:研究定喘顆粒治療毛細支氣管炎痰熱內蘊證的臨床效果。方法:選取2015年
4月-2017年4月本院收治的120例毛細支氣管炎痰熱內蘊證患兒,依據治療方法將其分為單獨西醫治療組(對照組)和西醫結合定喘顆粒治療組(觀察組),各60例。對兩組患兒的主要中醫癥候積分、臨床療效、不良反應發生情況進行統計分析。結果:觀察組的咳嗽、咳痰、哮鳴音積分及總分均顯著低于對照組(P<0.05);觀察組的治療總有效率為96.7%(58/60),顯著高于對照組的83.3%(50/60)(P<0.05);兩組不良反應發生率分別為6.7%(4/60)、3.3%(2/60),比較差異無統計學意義(P>0.05)。結論:定喘顆粒治療毛細支氣管炎痰熱內蘊證的臨床效果好,值得推廣應用。
【關鍵詞】 定喘顆粒; 毛細支氣管炎痰熱內蘊證; 臨床研究
Clinical Study of Dingchuan Granule in Treatment of Bronchiolitis Accumulation of Phlegm Heat Syndrome/ZHU Yan-ping,ZHAO Xia,MAO Shan-lin,et al.//Medical Innovation of China,2017,14(30):033-036
【Abstract】 Objective:To study the clinical effect of Dingchuan Granule in treatment of bronchiolitis accumulation of phlegm heat syndrome.Method:120 children with bronchiolitis accumulation of phlegm heat syndrome in our hospital from April 2015 to April 2017 were selected,according to the treatment methods,they were divided into western medicine alone treatment group(control group) and western medicine combined with Dingchuan Granule group(observation group),60 cases in each group.The main TCM symptoms integral,clinical efficacy and adverse reactions of two groups were statistically analyzed.Result:The cough,expectoration,wheezing scores and total score of observation group were significantly lower than those of control group(P<0.05),the total effective treatment of observation group was 96.7%(58/60),which was significantly higher than 83.3%(50/60) of control group(P<0.05),the incidence of adverse reactions was 6.7%(4/60) and 3.3%(2/60) respectively,but the difference was not statistically significant(P>0.05).Conclusion:The clinical effect of Dingchuan Granule in treatment of bronchiolitis accumulation of phlegm heat syndrome is good,it is worthy of popularization and application.
【Key words】 Dingchuan Granule; Bronchiolitis accumulation of phlegm heat syndrome; Clinical study
First-authors address:Nanjing University of TCM,Nanjing 210029,China
doi:10.3969/j.issn.1674-4985.2017.30.010
毛細支氣管炎是指6個月~2歲的嬰幼兒特有的呼吸道感染性疾病,冬春季的發病率較高。本病可造成流行,炎癥常可累及肺泡、肺泡壁和肺間質,是肺炎的一種特殊類型[1]。現有的西醫治療方法主要為抗感染、霧化及糖皮質激素的應用,治療周期長,且副作用大,往往短期內容易復發[2]。若配合中醫辨證用藥以止咳、平喘、解痙、調節體質為大法,能較快緩解癥狀、縮短療程、提高療效。緩解期若給予扶正固本、調節體質,可以減少復發,取得較好遠期療效。因此,開展中醫藥(定喘顆粒)治療毛細支氣管炎(痰熱內蘊證)的臨床療效評價研究不僅有學術價值,而且還對促進中西醫結合兒科發展,提高兒科醫師臨床技術水平具有重要意義[3]。本研究比較了單獨西醫與西醫結合定喘顆粒治療毛細支氣管炎痰熱內蘊證的臨床效果,現報道如下。……