《中國醫學影像技術》投稿須知(三)

《中國醫學影像技術》投稿須知(三)

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Shear-wave elastic modulus for differential diagnosis of benign and malignant breast lesions: Meta-analysis

DINGXinhua,XUPing,LEIHaiyan,WANGJiabing,TONGMinghui*,WANGHaiyong,TONGLei

(TheThirdDepartmentofUltrasound,LanzhouUniversitySecondHospital，Lanzhou730030，China)

Objective To assess the value of shear-wave elastic modulus for differential diagnosis of benign and malignant breast lesions using Meta-analysis. Methods Relevant Chinese and foreign articles about shear-wave elastography for differentiating benign and malignant breast lesions were collected from the literatures published before Apr.2016. Meta-analysis was conducted to assess the overall ability of the shear wave elastic modulus including Emax， Emea， Eratioand Esd. Results Totally 31 studies were brought into the Meta-analysis. The summarized sensitivity (SSEN) and summarized specificity (SSPE) of Emaxwere 0.87(95%CI [0.83， 0.91]) and 0.91 (95%CI [0.87， 0.93]). The SSEN and SSPE of Emeawere 0.84 (95%CI [0.77， 0.89]) and 0.88 (95%CI [0.84， 0.91]), The SSEN and SSPE of Eratiowere 0.88(95%CI [0.83， 0.91]) and 0.87 (95%CI [0.80， 0.91], the SSEN and SSPE of Esdwere 0.85 (95%CI [0.80， 0.89]) and 0.90 (95%CI [0.85， 0.94]). The summarized receiver operator characteristic analysis showed that the area under the curve of Emax， Emea， Eratioand Esdwere 0.95, 0.93, 0.93 and 0.93. Conclusion The shear wave elastic modulus contribute to differentiate benign and malignant breast lesions. Among these indices, Emaxis the best one.

Elasticity imaging techniques； Breast neoplasms； Meta-analysis

10.13929/j.1003-3289.201606167