妊娠期高血壓疾病（HDP）患者子宮動脈及胎兒臍動脈血流動力學(xué)變化與結(jié)局的探討

王瑩+黃海鳴+魯曉燕+劉穎蕾

[摘要] 目的 探討妊娠期高血壓疾病（HDP）患者子宮動脈及胎兒臍動脈血流動力學(xué)變化的關(guān)系。方法 方便選取2015年1月—2016年6月在該院進行常規(guī)孕檢的200例妊娠期高血壓疾病（HDP）患者作為研究組，另選同一時間段內(nèi)200名門診和病房孕檢產(chǎn)婦為對照組，2組患者均采用多普勒超聲檢查。比較2組患者血流動力學(xué)變化與胎兒情況及新生兒分娩結(jié)局的關(guān)系。結(jié)果 研究組患者子宮動脈PI（1.22±0.76）、RI（0.65±0.24）、S/D（29.04±0.18）明顯高于對照組（P<0.05）；胎兒臍動脈PI（0.92±0.07 ）、RI（0.62±0.06）、S/D（2.35±0.09）明顯高于對照組（P<0.05）；研究組胎兒雙頂徑（9.04±0.54）cm、頭圍（29.04±0.18）cm、股骨長度（6.87±0.52）cm、腹圍（29.60±1.86）cm；對照組胎兒雙頂徑（9.84±0.90）cm、頭圍（31.35±0.58）cm、股骨長度（7.58±0.46）cm、腹圍（34.04±1.34）cm。研究組胎兒雙頂徑、頭圍、股骨長度等情況明顯小于對照組（P<0.05）；研究組新生兒結(jié)局情況與對照組相比較差異有統(tǒng)計學(xué)意義（P<0.05）。結(jié)論 妊娠期高血壓不僅會影響母體子宮血液灌注情況，還會影響胎兒臍動脈血流量，嚴重阻礙胎兒宮內(nèi)生長，必須盡早采取有效措施予以診斷與治療。

[關(guān)鍵詞] 妊娠期高血壓疾病；子宮動脈；臍動脈；血流動力學(xué)

[中圖分類號] R5 [文獻標(biāo)識碼] A [文章編號] 1674-0742（2017）09（c）-0039-03

Study on Changes and Outcomes of Uterine Artery and Fetal Umbilical Artery Hemodynamics of HDP Patients

WANG Ying， HUANG Hai-ming， LU Xiao-yan， LIU Ying-lei

Department of Gynecology and Obstetrics， Nantong First Peoples Hospital， Nantong， Jiangsu Province， 226000 China

[Abstract] Objective To study the correlation between the uterine artery and fetal umbilical artery hemodynamics of HDP patients. Methods Convenient selection 200 cases of HDP patients with routine pregnancy examination in our hospital from January 2015 to June 2016 were selected as the research group， while 200 cases of outpatients and ward delivery women were selected as the control group， both groups adopted the colour Doppler ultrasound examiantion， and the changes of hemodynamics， fetal situation and delivery outcome of newborns were compared between the two groups. Results The uterine artery PI， RI and S/D in the research group were respectively （1.22±0.76）， （0.65±0.24）， （29.04±0.18）， which were obviously higher than those in the control group（P<0.05）， and the fetal umbilical artery PI， RI and S/D in the research group were respectively （0.92±0.07）， （0.62±0.06），（2.35±0.09）， which were obviously higher than those in the control group（P<0.05）， and the fetal biparietal diameter， head circumference， femur length， abdominal perimeter in the research group were obviously lower than those in the control group， [（9.04±0.54）cm， （29.04±0.18）cm， （6.87±0.52）cm， （29.60±1.86）cm vs （9.84±0.90）cm， （31.35±0.58）cm， （7.58±0.46）cm，（34.04±1.34）cm]（P<0.05）； the difference in the newborns outcome situation between the research group and the control group was statistically signfiicant（P<0.05）. Conclusion The hypertension during pregnancy can not affect the maternal uterus hemoperfusion but also affect the fetal umbilical artery blood flow and seriously prevent the fetal intrauterine growth， and we must adopt the effective measures for diagnosis and treatment as soon as possible.endprint