中國潰瘍性結腸炎診治指南（2023年·西安）

摘要 潰瘍性結腸炎（UC）病程遷延反復，涉及多個學科，規范化診療對提高UC的療效以及改善預后非常重要。近年來，我國在UC的基礎和臨床研究領域取得諸多進展，加之新的診療理念、新的治療藥物不斷應用于臨床，因此有必要更新UC診療共識意見，為廣大臨床工作者提供基于最新循證依據的診治指南。本指南由中華醫學會消化病學分會炎癥性腸病學組牽頭并聯合中國炎癥性腸病診療質量控制評估中心，結合國外最新共識、國內研究成果和實際情況，在2018年版炎癥性腸病診斷和治療共識意見的基礎上進行修訂。本指南的制定旨在反映當前UC臨床診治的最新理念和研究成果，為UC的臨床診治提供規范化指導意見。

關鍵詞 結腸炎，潰瘍性； 指南； GRADE分級； 德爾菲法

Chinese Clinical Practice Guideline on Management of Ulcerative Colitis （2023， Xi′an） Inflammatory Bowel Disease Group， Chinese Society of Gastroenterology， Chinese Medical Association; Inflammatory Bowel Disease Quality Control Center of China

Correspondence to： WU Kaichun， Department of Gastroenterology， the First Affiliated Hospital of Air Force Medical University， Xi′an （710032）， Email： kaicwu@fmmu.edu.cn; CHEN Minhu， Department of Gastroenterology， the First Affiliated Hospital， Sun Yat?sen University， Guangzhou （510080）， Email： chenminhu@mail.sysu.edu.cn; QIAN Jiaming， Department of Gastroenterology， Peking Union Medical College Hospital， Peking Union Medical College， Chinese Academy of Medical Sciences， Beijing （100730）， Email： qianjiaming1957@126.com

Abstract Ulcerative colitis （UC） is a chronic and prolonged condition spanning multiple disciplines. Standardized diagnostics and treatment are paramount for enhancing the therapeutic efficacy and improving the prognosis of UC. In the last a couple of years， substantial progress has been achieved in both basic and clinical research on UC in our country. The integration of novel diagnostic and therapeutic paradigms， new treatment modalities， have necessitated the update of consensus on UC management， offering imperative， evidence?based guidelines for health providers. This guideline， collaboratively developed by the Inflammatory Bowel Disease Group of Chinese Society of Gastroenterology， Chinese Medical Association， and the Inflammatory Bowel Disease Quality Control Center of China， incorporates the latest international consensus， domestic research findings， and practical considerations， as an update based on the 2018 Chinese consensus on diagnosis and treatment in inflammatory bowel disease. The formulation of this guideline aims to reflect the latest concepts and research findings in the clinical diagnosis and treatment of UC， providing standardized guidance for the clinical management of UC.

Key words Colitis， Ulcerative; Guideline; GRADE Approach; Delphi Technique

我國的診治共識意見在規范和提高炎癥性腸病（inflammatory bowel disease， IBD）臨床診治水平方面的作用不言而喻。隨著對IBD認識的加深，我國相關基礎和臨床研究更趨標準化和規范化，可用于制定共識指南的中國疾病人群數據也越來越多。有鑒于此，中華醫學會消化病學分會炎癥性腸病學組牽頭并聯合中國炎癥性腸病診療質量控制評估中心，在借鑒國外最新共識[1?7]的基礎上結合我國研究成果和實際情況，對我國2018年版IBD診斷和治療共識意見[8]進行修訂，將其分為潰瘍性結腸炎（ulcerative colitis， UC）和克羅恩病（Crohn′s disease， CD）兩部分，按指南制定標準收集分析證據，以問題式陳述的方式加以表達，力求使新的共識意見能更好地反映當前進展，內容更為深入全面，更具臨床指導價值。……