Helicobacter pylori promotes invasion and metastasis of gastric cancer by enhancing heparanase expression

Li-Ping Liu, Xi-Ping Sheng, Tian-Kui Shuai, Yong-Xun Zhao, Bin Li, Yu-Min Li

Abstract Correction to "Liu LP, Sheng XP, Shuai TK, Zhao YX, Li B, Li YM. Helicobacter pylori promotes invasion and metastasis of gastric cancer by enhancing heparanase expression. World J Gastroenterol 2018 ; 24 : 4565 -4577 [PMID: 30386106 DOI: 10 .3748 /wjg.v24 .i40 .4565 ]." In this article, we have identified some of the images in Figure 2 A, C, E, G, and I are identical to the images in Figures 1 B, 2 A,3 B, 3 E, and 3 G of another paper entitled "Liu L, Zhao Y, Fan G, Shuai T, Li B, Li Y.Helicobacter pylori infection enhances heparanase leading to cell proliferation via mitogenactivated protein kinase signalling in human gastric cancer cells.", which was published by us in the Molecular Medicine Reports in December, 2018 [PMID:30320396 DOI: 10 .3892 /mmr.2018 .9558 ]. The reason why we asked to replace the pictures was that when we were simultaneously preparing to submit our two different articles to the World Journal of Gastroenterology (WJG) and Molecular Medicine Reports, we uploaded the wrong pictures to the WJG, which were same as those submitted to the Molecular Medicine Reports. We apologize for this negligence and any inconvenience that this may cause. We would be grateful if you could replace the wrong pictures with the correct ones attached.

Key Words: Correction; Replace the wrong pictures; Gastric cancer; Helicobacter pylori

TO THE EDITOR

Correction

Correction to: Figure 2 A, C, E, G and I. Liu LP, Sheng XP, Shuai TK, Zhao YX, Li B, Li YM.Helicobacter pyloripromotes invasion and metastasis of gastric cancer by enhancing heparanase expression.World J Gastroenterol2018 ; 24 : 4565 -4577 [PMID:30386106 DOI: 10 .3748 /wjg.v24 .i40 .4565 ].

In this article[1 ], we have identified some of the images in Figure 2 A, C, E, G, and I are identical to the images in Figures 1 B, 2 A, 3 B, 3 E, and 3 G of another paper entitled"Liu L, Zhao Y, Fan G, Shuai T, Li B, Li Y.Helicobacter pyloriinfection enhances heparanase leading to cell proliferationviamitogenactivated protein kinase signalling in human gastric cancer cells"[2 ], which was published by us in theMolecular Medicine Reportsin December, 2018 .

The reason why we asked to replace the pictures was that when we were simultaneously preparing to submit our two different articles to theWorld Journal of Gastroenterology(WJG) andMolecular Medicine Reports, we uploaded the wrong pictures to theWJG, which were same as those submitted to theMolecular Medicine Reports.

We apologize for this negligence and any inconvenience that this may cause.

We would be grateful if you could replace the wrong pictures with the correct ones attached (Figure 1 ).

Figure 1 Heparanase protein expression following Helicobacter pylori infection in MKN-45 gastric cancer cells via the mitogen-activated protein kinase signaling pathway. A: Heparanase (HPA) expression was determined by Western blot at 0 , 6 , 12 , 24 , and 48 h after Helicobacter pylori (H.pylori) infection; B: Quantitative Western blot results of HPA; C: p-p38 mitogen-activated protein kinase (MAPK) expression was determined by Western blot at 0 , 30 ,60 , 120 , and 480 min after H. pylori infection; D: Quantitative Western blot results of p-p38 MAPK; E: HPA expression when the MAPK inhibitor SB203580 was given to MKN-45 cells before H. pylori infection; F: Quantitative Western blot results of HPA when the MAPK inhibitor SB203580 was given. bP ＜ 0 .01 compared with the value at 0 h; G and H: Cell invasion rates in the three groups detected using a Transwell invasion assay; I and J: Migration rates in the three groups detected using a scratch migration assay. aP ＜ 0 .05 , bP ＜ 0 .01 . HPA: Heparanase; MAPK: Mitogen-activated protein kinase; H. pylori: Helicobacter pylori. Figure 2 in the original manuscript: Liu LP, Sheng XP, Shuai TK, Zhao YX, Li B, Li YM. Helicobacter pylori promotes invasion and metastasis of gastric cancer by enhancing heparanase expression. World J Gastroenterol 2018 ; 24 : 4565 -4577 [PMID: 30386106 DOI: 10 .3748 /wjg.v24 .i40 .4565 ].

ACKNOWLEDGEMENTS

在過(guò)去很長(zhǎng)一段時(shí)間中，傳統(tǒng)高校圖書(shū)館資源形式大多為紙質(zhì)書(shū)籍、報(bào)刊、文獻(xiàn)等。但在大數(shù)據(jù)時(shí)代到來(lái)以后，這種傳統(tǒng)高校圖書(shū)館資源形式被完全打破，高校圖書(shū)館的資源形式也變得越來(lái)越多。使用大數(shù)據(jù)技術(shù)后的高校圖書(shū)館，不僅具備館藏紙質(zhì)文獻(xiàn)等傳統(tǒng)資源，還在此基礎(chǔ)上增設(shè)了云上存儲(chǔ)資源、網(wǎng)絡(luò)資源等，使高校圖書(shū)館資源形式不再局限于紙質(zhì)化。與此同時(shí)，高校圖書(shū)館在使用大數(shù)據(jù)技術(shù)之后，用戶在瀏覽高校圖書(shū)館網(wǎng)站之后產(chǎn)生的信息也將成為高校圖書(shū)館大數(shù)據(jù)資源的組成部分。

We thank Dr. Zhong-Tian Bai for his critical reading of this manuscript. The authors appreciate Wen-Ting He for technical assistance.