胎膜早破型先兆流產(chǎn)患者應(yīng)用利托君治療的臨床效果及對(duì)保胎成功率影響

王紅麗

【摘要】 目的：探究胎膜早破型先兆流產(chǎn)患者應(yīng)用利托君治療的臨床效果及對(duì)保胎成功率的影響。方法：將2017年2月-2019年2月筆者所在醫(yī)院收治的86例胎膜早破型先兆流產(chǎn)患者作為研究對(duì)象，采用隨機(jī)數(shù)字表法將其平均分為兩組，每組43例。對(duì)照組應(yīng)用硫酸鎂進(jìn)行治療，試驗(yàn)組應(yīng)用利托君進(jìn)行治療。對(duì)比兩組治療效果。結(jié)果：試驗(yàn)組保胎成功率顯著高于對(duì)照組，差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。試驗(yàn)組患者宮縮消失時(shí)間、孕齡延長(zhǎng)時(shí)間均顯著優(yōu)于對(duì)照組，差異有統(tǒng)計(jì)學(xué)意義（P<0.05）。結(jié)論：采用利托君對(duì)胎膜早破型先兆流產(chǎn)患者進(jìn)行治療，能夠提升保胎成功率，縮短患者宮縮消失時(shí)間，延長(zhǎng)孕齡。

【關(guān)鍵詞】 胎膜早破型; 先兆流產(chǎn); 利托君; 保胎成功率

doi：10.14033/j.cnki.cfmr.2019.22.016 文獻(xiàn)標(biāo)識(shí)碼 B 文章編號(hào) 1674-6805（2019）22-00-03

【Abstract】 Objective：To explore the clinical effect of Ritodrine treatment on the success rate of premature rupture of membranes with threatened abortion.Method：A total of 86 cases of threatened abortion with premature rupture of membranes admitted to our hospital from February 2017 to February 2019 were selected as the research objects，and they were divided into two groups by random number table method on average，with 43 cases in each group.The control group was treated with Magnesium Sulfate，while the experimental group was treated with Ritodrine.The therapeutic effects of the two groups were compared.Result：The success rate of fetal protection in the experimental group was significantly higher than that in the control group，and the difference was statistically significant（P<0.05）.The time of uterine contraction disappearance and gestational age prolongation in the experimental group were significantly better than those in the control group，the differences were statistically significant（P<0.05）.Conclusion：Using Ritodrine to treat threatened threatened abortion with premature rupture of membranes can improve the success rate of fetal preservation，shorten the time of disappearance of contractions，and prolong the gestational age.

【Key words】 Premature rupture of membranes; Threatened abortion; Ritodrine; Success rate of fetal protection

First-authors address：Peoples Hospital of Songzi City，Songzi 434200，China

所謂先兆流產(chǎn)，指的是產(chǎn)婦在妊娠28周之前，陰道內(nèi)出現(xiàn)少量出血，患者會(huì)出現(xiàn)繼發(fā)性的下腹部疼痛和腰部疼痛，對(duì)患者的盆腔進(jìn)行檢查，患者宮口并未完全打開(kāi)，且陰道內(nèi)無(wú)妊娠物流出，患者的子宮大小與孕周情況相符，若未及時(shí)采取措施進(jìn)行干預(yù)，則會(huì)導(dǎo)致難免流產(chǎn)情況的出現(xiàn)，先兆流產(chǎn)患者大都會(huì)出現(xiàn)月經(jīng)停止、陰道出血和腹部疼痛的病癥[1]。據(jù)研究，其患病因素大多與胎膜早破相關(guān)，胎膜早破型先兆流產(chǎn)患者，由于在生產(chǎn)前出現(xiàn)胎膜自然破裂現(xiàn)象，其主要與創(chuàng)傷、宮頸內(nèi)口松弛、感染、羊膜腔內(nèi)壓力升高等多種因素相關(guān)[2]，胎膜早破型先兆流產(chǎn)患者及胎兒的生命健康均會(huì)受到嚴(yán)重不良影響[3]。所以必須及時(shí)采取措施進(jìn)行治療干預(yù)，本研究就胎膜早破型先兆流產(chǎn)患者應(yīng)用利托君治療的臨床效果及保胎成功率的影響進(jìn)行分析，現(xiàn)報(bào)道如下。

1 資料與方法

1.1 一般資料

將2017年2月-2019年2月筆者所在醫(yī)院收治的86例胎膜早破型先兆流產(chǎn)患者作為研究對(duì)象，納入標(biāo)準(zhǔn)：兩組患者均經(jīng)臨床診斷確診為胎膜早破型先兆流產(chǎn)的患者;年齡均在18歲以上[4]。排除標(biāo)準(zhǔn)：嚴(yán)重心腦血管疾病的患者，腎臟功能衰竭的患者，多胎妊娠的患者，合并其他嚴(yán)重產(chǎn)科疾病的患者[5]。采用隨機(jī)數(shù)字表法將其平均分為兩組，每組43例。試驗(yàn)組患者年齡20～41歲，平均（29.63±2.11）歲;孕周20～28周，平均（23.23±1.45）周。對(duì)照組患者年齡21～42歲，平均（29.33±2.09）歲;孕周21～28周，平均（23.61±1.25）周。兩組患者一般資料比較，差異無(wú)統(tǒng)計(jì)學(xué)意義（P>0.05），有可比性。