血清降鈣素原水平評價早產兒院內感染程度與預后的研究

彭華

[摘要] 目的 研究血清降鈣素原水平評價早產兒院內感染程度與預后。 方法 方便選取2018年1月—2016年1月在該院發生院內感染的68例早產兒作為研究對象，均對其進行血清降鈣素原水平檢測，根據檢測結果將其分為輕度感染組、中度感染組和重度感染組，對3組患兒的新生兒危重評分進行測定，并對3組患兒的預后效果進行觀察分析。 結果 通過68例患兒的血清降鈣素原水平評價分析，26例為輕度感染組，23例為中度感染組，19例為重度感染組，重度感染組的血清降鈣素原水平均高于輕度感染組和中度感染組，中度感染組的血清降鈣素原水平高于輕度感染組，差異有統計學意義（P<0.05）。比較3組患兒的新生兒危重評分發現，重度感染組的評分均低于輕度感染組和中度感染組，中度感染組的評分低于輕度感染組，差異有統計學意義（P<0.05）。比較3組患兒的預后情況發現，輕度感染組的存活率均高于中度感染組和重度感染組，中度感染組的存活率高于重度感染組，組間差異有統計學意義（P<0.05）。 結論 通過對發生院內感染早產兒血清降鈣素原水平分析可對其感染程度進行有效鑒別區分，從不同感染程度的患兒預后情況觀察發現，感染越嚴重患兒的存活率越低。

[關鍵詞] 血清降鈣素原水平；早產兒；院內感染；新生兒危重評分

[中圖分類號] R446 [文獻標識碼] A [文章編號] 1674-0742（2019）02（b）-0010-03

Serum Procalcitonin Level Evaluation of Nosocomial Infection and Prognosis in Preterm Infants

PENG Hua

Department of Neonatology， Chongzuo People's Hospital， Chongzuo， Guangxi， 532200 China

[Abstract] Objective To study the serum procalcitonin level and evaluate the degree of nosocomial infection and prognosis in premature infants. Methods 68 premature infants with nosocomial infection in our hospital were selected as subjects from January 2016 to January 2018. All of them were tested for serum procalcitonin level. According to the test results， they were divided into mild infection group， moderate infection group and severe infection group. The neonatal critical scores of the three groups were measured， and the prognostic effects of the three groups were observed and analyzed. Results Serum procalcitonin levels were evaluated in 68 children， 26 were mild infection， 23 were convenient moderately infected， 19 were severely infected， and serum procalcitonin was high in severely infected group. In the mild infection group and the moderate infection group， the serum procalcitonin level in the moderate infection group was higher than that in the mild infection group. The difference between the groups was significant（P<0.05）. Comparing the neonatal critical scores of the three groups， the scores of the severe infection group were lower than those of the mild infection group and the moderate infection group. The scores of the moderate infection group were lower than those of the mild infection group. The differences between the groups were significant（P<0.05）. Comparing the prognosis of the three groups， the survival rate of the mild infection group was higher than that of the moderate infection group and the severe infection group. The survival rate of the moderate infection group was higher than that of the severe infection group. Differences between groups were significant（P<0.05）. Conclusion By analyzing the serum procalcitonin level in premature infants with nosocomial infection， the degree of infection can be effectively differentiated. The prognosis of children with different infection levels shows that the more severe the infection， the lower the survival rate.