詞語識別認(rèn)知過程中的腦功能網(wǎng)絡(luò)研究

摘 ?要： 詞語識別是心理語言學(xué)研究領(lǐng)域的一個重要方面，基于腦功能網(wǎng)絡(luò)連接模式的研究有助于對其神經(jīng)機制的揭示。本文基于開源詞語識別fMRI實驗數(shù)據(jù)，首先利用人腦解剖學(xué)模板AAL分別構(gòu)建真詞試驗時和輔音字符串試驗時的腦功能網(wǎng)絡(luò)，然后采用圖論分析中的度中心性對AAL中的90個腦區(qū)進(jìn)行活躍度度量，最后使用T檢驗對兩種試驗條件下各腦區(qū)的活躍度進(jìn)行了統(tǒng)計對比。實驗結(jié)果顯示，真詞試驗時腦功能網(wǎng)絡(luò)中分布在距狀裂周圍皮層、舌回、枕上回、枕中回、枕下回、頂上回的9個腦區(qū)的度中心性顯著高于輔音字符串試驗時的情況。實驗結(jié)果表明，人腦在識別具有語義信息的詞語時，大腦皮層的各個區(qū)域更加趨于協(xié)作，顯著活躍的腦區(qū)能夠作為詞語識別進(jìn)一步研究的生物標(biāo)記。

關(guān)鍵詞： 詞語識別;腦功能網(wǎng)絡(luò);圖論分析;度中心性

中圖分類號： TP391. 41 ? ?文獻(xiàn)標(biāo)識碼： A ? ?DOI：10.3969/j.issn.1003-6970.2019.12.025

本文著錄格式：何享，張笑非. 詞語識別認(rèn)知過程中的腦功能網(wǎng)絡(luò)研究[J]. 軟件，2019，40（12）：110114

Research on Functional Brain Network in Cognitive Process of Word Recognition

HE Xiang1， ZHANG Xiao-fei2，3*

（1. School of Foreign Language， Jiangsu University of Science and Technology， Zhenjiang 212003， China;

2. Faculty of Information， Beijing University of Technology， Beijing 100124， China;

3. School of Computer， Jiangsu University of Science and Technology， Zhenjiang 212003， China）

【Abstract】： Word recognition is an important aspect in the field of psycholinguistic research. The research based on connectivity pattern of functional brain network is helpful to reveal its neural mechanism. Based on the fMRI experimental data of open source word recognition， the brain anatomical template of AAL was used to construct the functional brain networks of real word trials and the consonant string trials respectively. Degree centrality in graph theoretical analysis was adopted to measure the activities of the 90 brain regions in the AAL. The activities of each brain region under the two trials were statistically compared with T-test at last. The experimental results showed that the degree centralities of nine brain regions distributed in cerebral cortex， including calcarine cortex， lingual gyrus， occipital superior gyrus， occipital middle gyrus， occipital inferior gyrus and parietal superior gyrus during real word trials， are significantly higher than those during consonant string trials. The final results indicate that when human brain recognizes words with semantic information， the various regions of the cerebral cortex tend to have a more integrating collaboration， and the significantly active brain regions can be used as biomarkers for further research on word recognition.

【Key words】： Word recognition; Functional brain network; Graph theoretical analysis; Degree centrality

0 ?引言

人腦詞語識別的神經(jīng)機制是認(rèn)知研究領(lǐng)域一個非常具有挑戰(zhàn)性的問題。在詞語識別的認(rèn)知過程中，大腦會在幾分之一秒內(nèi)從大量的存儲區(qū)域中檢索當(dāng)前詞語的信息，并以極其靈活的方式對這些信息進(jìn)行組合。基于人腦語言處理經(jīng)典神經(jīng)學(xué)模型的研究，發(fā)現(xiàn)有助于詞語識別的神經(jīng)網(wǎng)絡(luò)只涉及少數(shù)的一些腦區(qū)，例如左下額葉，左下顳，角回等腦區(qū)[1-3]。許多研究基于視覺呈現(xiàn)的詞語識別實驗收集數(shù)據(jù)并進(jìn)行了分析。……