彭田川 劉鋒
[摘要] 目的 探討在輸血工作中應用血清不規則抗體檢測的臨床效果。方法 應用隨機數字法,從該院2016年8月—2017年8月接收的輸血患者中方便抽取340例作為該次研究的對象,所有患者均在輸血前先展開血清不規則抗體檢測,觀察其結果。 結果 ①陽性不規則抗抗體共3例,檢出率是0.88%。其余337例均為陰性患者,比例是99.12%,陰性與陽性檢出率對比差異有統計學意義(P<0.05)。②3例陽性患者中,2例患者為Rh系統抗體陽性,比例是66.67%,包括了抗-E抗體與抗-DC抗體各1例;另外1例為MNS系統抗-M抗體陽性,所占比例是33.33%,比較差異有統計學意義(P<0.05)。結論 在輸血工作中采取抗人球蛋白法進行血清不規則抗體檢測,能夠提升檢出率的準確性,明確患者的不規則抗體類型,能夠提升臨床輸血效果,值得推廣與使用。
[關鍵詞] 輸血工作;血清;不規則抗體;檢測;臨床效果
[中圖分類號] R446 [文獻標識碼] A [文章編號] 1674-0742(2018)03(a)-0184-03
Clinical Analysis of Serum Irregular Antibody in Transfusion
PENG Tian-chuan, LIU Feng
Department of Transfusion, Banan District Peoples Hospital of Chongqing, Chongqing, 401320 China
[Abstract] Objective This paper tries to discuss the clinical effect of detecting serum irregular antibody in blood transfusion. Methods Randomized digital method was conveniently selected 340 cases of transfusion patients from August 2016 to August 2017 in this hospital. All patients were tested for irregular serum antibodies before observing the transfusion results. Results ①A total of 3 positive anti-anti-body antibodies, the detection rate was 0.88%. The remaining 337 cases were negative patients, the proportion was 99.12%, negative and positive detection rate was statistically significant (P<0.05). ②Of 3 positive patients, 2 were positive for Rh system antibody, the ratio was 66.67%, including 1 anti-E antibody and anti-DC antibody; the other 1 was positive for MNS system anti-M antibody, the proportion was 33.33%, which was statistically significant (P<0.05). Conclusion In the blood transfusion to take anti-human globulin method to detect irregular serum antibodies, can improve the accuracy of the detection rate, identify patients with irregular antibody types, can enhance clinical transfusion, it is worth promoting and use.
[Key words] Blood transfusion; Serum; Irregular antibodies; Detection; Clinical effect
在臨床救治工作中,輸血已經成為治療疾病及挽救患者生命安全的重要措施,在具體操作中需要謹慎對待,否則一旦出現問題均會對治療效果造成影響,甚至威脅患者的生命安全,與此同時,輸血工作人員還需具備精湛的操作技能,提高輸血的及時性和準確性[1]。值得注意的是,在為患者開展輸血治療之前,需要對其血性免疫抗體進行篩查,通過篩查結果將不同血型免疫抗體排除,這對于保障患者的健康與安全均有重要意義。另外,在人體中,血型抗體存在不規則與規則之分,規則抗體主要是指人體基本血型如A型、B型、O型中的抗-A、抗-B、抗-AB等,而不規則血型抗體則主要是指超越基本血型抗體之外的免疫抗體,包括IgG、IGM等抗體[2]。因此,要想提高輸血效率,降低患者的不良反應,加強血清不規則抗體檢測十分關鍵,為了進一步提升該檢測在臨床輸血工作的臨床價值與效果,該次研究從該院2016年8月—2017年8月接收的輸血患者中方便抽取340例展開詳細分析,現報道如下?!?br>