普米克令舒聯合氨溴索治療新生兒肺炎的臨床療效觀察

史貽芳

摘 要：目的 觀察普米令舒聯合氨溴索治療新生兒肺炎的臨床療效，評價其臨床應用價值。方法 選取我院2016年3月～2017年4月收治的114例肺炎新生兒，隨機分為研究組與常規組，各57例。所有患兒均實施營養補充、預防感染、吸氧措施等基礎治療，在此前提下常規組患兒采用普米克令舒治療，研究組在此基礎上加用氨溴索，觀察兩組患兒的治療效果、住院時間、咳嗽消失時間、肺啰音消失時間、治療有效率及家長滿意度。結果 研究組治療總有效率優于常規組（96.48% vs 82.46%），組間比較差異有統計學意義（P<0.05）；研究組患兒的咳嗽消失時間、肺啰音消失時間、退熱時間、吸氧時間及住院時間均優于常規組，差異有統計學意義（P<0.05）；研究組患兒家長治療滿意度高于常規組（98.25% vs 87.72%），差異有統計學意義（P<0.05）。結論 采用普米令舒聯合氨溴索治療新生兒肺炎，臨床療效顯著，患兒癥狀消退快，家長滿意度高，值得臨床應用推廣。

關鍵詞：普米克令舒；氨溴索；新生兒肺炎

中圖分類號：R722.1 文獻標識碼：A DOI：10.3969/j.issn.1006-1959.2018.04.047

文章編號：1006-1959（2018）04-0132-02

Abstract：Objective To observe the clinical effect of Pulmicort combined with Ambroxol in the treatment of neonatal pneumonia，and to make an evaluation of its clinical application value.Methods From March 2016 to April 2017，114 newborns with pneumonia were randomly divided into study group and routine group，57 cases of each group.All children were given nutritional supplement，infection prevention，oxygen inhalation measures and other basic treatment，the routine group was treated with Pulmicort and the study group was treated with ambroxol on the above basis.The therapeutic effects，length of hospital stay，disappearance of cough，disappearance of pulmonary rales，treatment efficiency and parents' satisfaction were observed in both groups.Results The total effective rate of the study group was better than that of the routine group（96.48%vs82.46%），there was significant difference between the two groups（P< 0.05），and the time of cough disappearance，lung rale disappearance，antipyretic time，oxygen absorption time and hospitalization time in the study group were better than those in the routine group，the difference was statistically significant（P<0.05），the satisfaction of the parents in the study group was higher than that of the routine group（98.25%vs87.72%），and the difference was statistically significant （P<0.05）.Conclusion The clinical efficacy of Pulmicort combined with ambroxol in the treatment of neonatal pneumonia is significant. The symptoms of children are rapidly subsided and their parents' satisfaction is high，which is worthy of clinical application and promotion.

Key words：Pulmicort；Ambroxol；Neonatal pneumonia

新生兒肺炎（neonatal pneumonia）在臨床上較為常見，具體表現為患兒口吐白沫、哭鬧不安、呼吸急促、口周發青、精神萎靡等，影響新生兒的生長發育，嚴重的甚至導致患兒死亡。新生兒肺炎根據病因不同可分為兩種，一種為感染性肺炎，另一種則為吸入性肺炎。臨床研究表明，吸入性肺炎治療不當會演變為感染性肺炎，治療時應格外重視。本次研究采用普米克令舒聯合氨溴索治療我院2016年3月～2017年4月收治的114例肺炎新生兒，取得滿意療效，現報告如下。

1 資料與方法

1.1一般資料 選取我院2016年3月～2017年4月收治的114例肺炎新生兒，隨機分為研究組與常規組，各57例。研究組中男29例，女28例，日齡18～36 h，平均日齡（30.78±4.29）h，體質量3.31～5.16 kg，平均體質量（3.81±0.38）kg，乳汁吸入肺炎6例，胎糞吸入肺炎12例，羊水吸入肺炎14例，感染性肺炎25例；常規組中男31例，女26例，日齡20～36 h，平均日齡（31.26±4.17）h，體質量3.45～5.52 kg，平均體質量（3.91±0.41）kg，乳汁吸入肺炎5例，胎糞吸入肺炎13例，羊水吸入肺炎15例，感染性肺炎24例。兩組患兒日齡、體質量及肺炎類型比較差異無統計學意義（P>0.05），臨床可比。