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超氧化物歧化酶的生物學效應(yīng)和在血管性疾病中的作用

2013-11-20 08:28:58吉林大學白求恩第一醫(yī)院心血管診治中心吉林長春3002
中國老年學雜志 2013年4期
關(guān)鍵詞:生物學效應(yīng)

陳 珊 程 熠 劉 全 (吉林大學白求恩第一醫(yī)院心血管診治中心,吉林 長春 3002)

1 SOD的生物學效應(yīng)

2 SOD在血管性疾病中的作用

3 SOD與血管重構(gòu)

4 未來方向

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6 Rhee SG.Cell signaling.H2O2,a necessary evil for cell signaling〔J〕.Science,2006;312:1882-3.

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9 Li Q,Harraz MM,Zhou W,et al.Nox2 and Rac1 regulate H2O2-dependent recruitment of TRAF6 to endosomal interleukin-1 receptor complexes〔J〕.Mol Cell Biol,2006;26:140-54.

10 Bienert GP,Moller AL,Kristiansen KA,et al.Specific aquaporins facilitate the diffusion of hydrogen peroxide across membranes〔J〕.J Biol Chem,2007;282:1183-92.

11 Hawkins BJ,Madesh M,Kirkpatrick CJ,et al.Superoxide flux in endothelial cells via the chloride channel-3 mediates intracellular signaling〔J〕.Mol Biol Cell,2007;18:2002-12.

12 Miller FJ Jr,F(xiàn)ilali M,Huss GJ,et al.Cytokine activation of nuclear factor kappa B in vascular smooth muscle cells requires signaling endosomes containing Nox1 and ClC-3〔J〕.Circ Res,2007;101:663-71.

13 Mumbengegwi DR,Li Q,Li C,et al.Evidence for a superoxide permeability pathway in endosomal membranes〔J〕.Mol Cell Biol,2008;28:3700-12.

14 Alvarez B,Demicheli V,Duran R,et al.Inactivation of human Cu,Zn superoxide dismutase by peroxynitrite and formation of histidinyl radical〔J〕.Free Radic Biol Med,2004;37:813-22.

15 Ischiropoulos H,Zhu L,Chen J,et al.Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase〔J〕.Arch Biochem Biophys,1992;298:431-7.

16 MacMillan-Crow LA,Crow JP,Kerby JD,et al.Nitration and inactivation of manganese superoxide dismutase in chronic rejection of human renal allografts〔J〕.Proc Natl Acad Sci U S A,1996;93:11853-8.

17 Leite PF,Danilovic A,Moriel P,et al.Sustained decrease in superoxide dismutase activity underlies constrictive remodeling after balloon injury in rabbits〔J〕.Arterioscler Thromb Vasc Biol,2003;23:2197-202.

18 Hink HU,Santanam N,Dikalov S,et al.Peroxidase properties of extracellular superoxide dismutase:role of uric acid in modulating in vivo activity〔J〕.Arterioscler Thromb Vasc Biol,2002;22:1402-8.

19 Balaban RS,Nemoto S,F(xiàn)inkel T.Mitochondria,oxidants,and aging〔J〕.Cell,2005;120:483-95.

20 Murphy MP.How mitochondria produce reactive oxygen species〔J〕.Biochem J,2009;417:1-13.

21 Zorov DB,Juhaszova M,Sollott SJ.Mitochondrial ROS-induced ROS release:an update and review〔J〕.Biochim Biophys Acta,2006;1757:509-17.

22 Ghafourifar P,Richter C.Nitric oxide synthase activity in mitochondria〔J〕.FEBS Lett,1997;418:291-6.

23 Giulivi C,Poderoso JJ,Boveris A.Production of nitric oxide by mitochondria〔J〕.J Biol Chem,1998;273:11038-43.

24 Brown GC,Cooper CE.Nanomolar concentrations of nitric oxide reversibly inhibit synaptosomal respiration by competing with oxygen at cytochrome oxidase〔J〕.FEBS Lett,1994;356:295-8.

25 Cleeter MW,Cooper JM,Darley-Usmar VM,et al.Reversible inhibition of cytochrome c oxidase,the terminal enzyme of the mitochondrial respiratory chain,by nitric oxide.Implications for neurodegenerative diseases〔J〕.FEBS Lett,1994;345:50-4.

26 Stocker R,Keaney JF Jr.Role of oxidative modifications in atherosclerosis〔J〕.Physiol Rev,2004;84:1381-478.

27 Nelson SK,Bose SK,McCord JM.The toxicity of high dose superoxide dismutase suggests that superoxide can both initiate and terminate lipid peroxidation in the reperfused heart〔J〕.Free Radic Biol Med,1994;16:195-200.

28 Cathcart MK,McNally AK,Morel DW,et al.Superoxide anion participation in human monocytemediated oxidation of low-density lipoprotein and conversion of low-density lipoprotein to a cytotoxin〔J〕.J Immunol,1989;142:1963-9.

29 White CR,Brock TA,Chang LY,et al.Superoxide and peroxynitrite in atherosclerosis〔J〕.Proc Natl Acad Sci U S A,1994;91:1044-8.

30 Lehr HA,Becker M,Marklund SL,et al.Superoxide-dependent stimulation of leukocyte adhesion by oxidatively modified LDL in vivo〔J〕.Arterioscler Thromb,1992;12:824-9.

31 Madamanchi NR,Moon SK,Hakim ZS,et al.Differential activation of mitogenic signaling pathways in aortic smooth muscle cells deficient in superoxide dismutase isoforms〔J〕.Arterioscler Thromb Vasc Biol,2005;25:950-6.

32 Papaharalambus CA,Griendling KK.Basic mechanisms of oxidative stress and reactive oxygen species in cardiovascular injury〔J〕.Trends Cardiovasc Med,2007;17:48-54.

33 Makino A,Skelton MM,Zou AP,et al.Increased renal medullary oxidative stress produces hypertension〔J〕.Hypertension,2002;39:667-72.

34 Kopkan L,Castillo A,Navar LG,et al.Enhanced superoxide generation modulates renal function in ANG Ⅱ-induced hypertensive rats〔J〕.Am J Physiol Renal Physiol,2006;290:F80-6.

35 Papaharalambus CA,Griendling KK.Basic mechanisms of oxidative stress and reactive oxygen species in cardiovascular injury〔J〕.Trends Cardiovasc Med,2007;17:48-54.

36 Brasen JH,Leppanen O,Inkala M,et al.Extracellular superoxide dismutase accelerates endothelial recovery and inhibits instent restenosis in stented atherosclerotic Watanabe heritable hyperlipidemic rabbit aorta〔J〕.J Am Coll Cardiol,2007;50:2249-53.

37 Laukkanen MO,Kivela A,Rissanen T,et al.Adenovirus-mediated extracellular superoxide dismutase gene therapy reduces neointima formation in balloondenuded rabbit aorta〔J〕.Circulation,2002;106:1999-2003.

38 Ozumi K,Tasaki H,Takatsu H,et al.Extracellular superoxide SOD and vascular disease 1603 dismutase overexpression reduces cuff-induced arterial neointimal formation〔J〕.Atherosclerosis,2005;181:55-62.

39 Leite PF,Danilovic A,Moriel P,et al.Sustained decrease in superoxide dismutase activity underlies constrictive remodeling after balloon injury in rabbits〔J〕.Arterioscler Thromb Vasc Biol,2003;23:2197-202.

40 Agrawal RS,Muangman S,Layne MD,et al.Preemptive gene therapy using recombinant adeno-associated virus delivery of extracellular superoxide dismutase protects heart against ischemic reperfusion injury,improves ventricular function and prolongs survival〔J〕.Gene Ther,2004;11:962-9.

41 Vozenin-Brotons MC,Sivan V,Gault N,et al.Antifibrotic action of Cu/Zn SOD is mediated by TGF-beta1 repression and phenotypic reversion of myofibroblasts〔J〕.Free Radic Biol Med,2001;30:30-42.

42 Salvemini D,Riley DP,Cuzzocrea S.SOD mimetics are coming of age〔J〕.Nat Rev Drug Discov,2002;1:367-74.

43 Heistad DD.Gene therapy for vascular disease〔J〕.Vasc Pharmacol,2006;45:331-3.

44 Muzykantov VR.Targeting of superoxide dismutase and catalase to vascular endothelium〔J〕.J Control Rel,2001;71:1-21.

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