Clinical Application of Photopic Negative Response of the Flash Electroretinogram in Primary Open-angle Glaucoma

Lina Huang， Xiaoli Shen， Ning Fan， Jing He

Shenzhen Eye Hospital， Jinan University， Shenzhen 518040， China

Introduction

Materials and methods

Study subjects

ERG recordings

Visual field analyses

SD-OCT

Statistical analysis

Results

ComparisonbetweenthenormalandPOAG groups

Table 1 Demographic and clinical data for this study

Figures 1，2，3，4 Comparison of a-waves， b-waves and photopic negative responses （PhNRs） among the four groups

Correlation between the PhNR and other parameters

Table 2 The correlation coefficient between the PhNR and other parameters

Figure 5 The scatter plots of PhNR amplitude and MD

Figure 6 The scatter plots of PhNR amplitude and mRNFL

Figure 7 The scatter plots of PhNR amplitude and PSD

Sensitivity and specificity of the PhNR in early POAG

Table 3 The ROC curves analysis between the early POAG group and normal group

Figure 8 Receiver operating characteristic（ROC）curves for PhNR，a-and b-wave amplitudes

Discussion