Comparison of the Diagnostic Ability of Retinal Nerve Fiber Layer Thickness Measured using Time Domain and Spectral Domain Optical Coherence Tomography in Primary Open Angle Glaucoma

Lina Huang，Ning Fan，Xiaoli Shen，Jing He

Shenzhen Eye Hospital，Jinan University， Shenzhen 518034，China

Methods

Results

Table 1 Clinical characteristics of the normal， early POAG and PPG groups （x±s）

Table 2 Comparison of retinal nerve fiber layer（RNFL） thickness measurement by Stratus OCT and Cirrus HD－OCT（x±s，μm）

Table 3 Correlation of retinal nerve fiber layer（RNFL）thickness measurement on average and each quadrant usingStratus OCT and Cirrus HD－OCT

Figure 1 Scatter plot and regression line shows the correlation of average retinal nerve fiber layer （RNFL） thickness measurements between Stratus OCT and Cirrus HD－OCT．

Figure 2 Bland-Altman plot of the agreement of average RNFL thickness （ARNFLT） measurements between Stratus OCT and Cirrus HD-OCT， with the mean difference-11．8 μm （solid line） and 95%limits of agreement（dashed line）．

Table 4 Diagnostic accuracy of Cirrus HD－OCT and Stratus OCT Parameters in PPG and normal groups

Figure 3 ROC curves of the average， superior and inferior quadrants RNFL thickness parameters from the Cirrus HDOCT and Stratus OCT in PPG and normal groups．

Table 5 Diagnostic accuracy of Cirrus HD－OCT and Stratus OCT parameters in early POAG and normal groups

Discussion

Figure 4 ROC curves of the average， superior and inferior quadrants RNFL thickness parameters from the Cirrus HDOCT and Stratus OCT in early POAG and normal groups．

Figure 5 Venn diagrams show the overlap between abnormal RNFL thicknesses measured using Cirrus HD－OCT and Stratus OCT in both early POAG and PPG groups．