Comparison on Clinical Characteristics of Multifocal Choroiditis and Punctate Inner Choroidopathy

Zhaomeng Shen，linyi Zhang，Zhiguo Li，Xian Zhang，Hongbo Cui

Lihuili Hospital of Ningbo，Ningbo 315040，China

Materials and methods

Statistical analysis

Results

Table 1 Patient-specific characteristics in MFC and PIC

Table 2 Eye-specific characteristics at presentation in MFC and PIC

Discussion

Figure 1 （a） Fundus color photography of a 34-year old female PIC patient．Multiple， samll， yellow chorioretinal lesions in macula， typically 100－300 μm in size（white arrows）．A gray subretinal fibrosis is seen juxtafoveal（yellow arrow）．（b） In the early phase of FA，the PIC lesions can have a variable fluorescence pattern．In the scarred and healed lesions the choriocapillaris is damaged， there is hypof orescence （hollow white arrows）．While purely RPE atropy there is window defect with hyperfluorescence （white arrows）．Irregular hyperfluorescence is seen at the site of CNV （yellow arrow） （c）In the early phase of ICGA，．clearly shows the areas of poor blood flow in the choriocapillaris．In the area of the lesions there is hypofluorescence （white arrows）．．（d）In the late phase of FA，．there is staining of the lesions，．making them appear hyperfluorescent（white arrows）．Mild leakage of dye from CNV（yellow arrow）．（e） In the late phase of ICGA， hypofluorescence still can be seen in the site of atrophic choriocapillaris，around the hypofluorescence，there are hyperfluorescence areas associated with the localized vasculitis of choriocapillaris（white arrows）．

Figure 2 （a） （b）Fundus color photographies of a 24-year old male MFC patient，．bilateral eyes areaffected，．CNV can be seen inferior to fovea （yellow arrow）．（c） In the early phase of FA，the the scarred lesions display hypofluorescence（white arrows），．active lesions with hyperfluorescence leakaging from injured blood-renital barrier（white arrows hollow）．Irregular hyperfluorescence is seen at the site of CNV （yellow arrow）．（d、f） Obvious hypofluorescence （white arrows）in the early and late phase of ICGA， corresponded to the localized choroidal hypoperfusion．．（e）．In the late fhase of FA，demostrates multiple small ares of hyperfluorescence due to stain of MFC lesions．（white arrow），．leakage from an active CNV is detected．（yellow arrow），．mild leakage and stain from retinal vessel walls is the evidence of intraocular inflammation．