
【中圖分類號】 R651 【文獻標志碼】 A 【文章編號】 1672-7770(2025)03-0259-04
Abstract: ObjectiveTo explore the clinical characteristics trigeminal neuralgia without vascular deompression and the therapeutic effects trigeminal nerve combing. MethodsA total 455 patients with primary trigeminal neuralgia(TN) underwent microvascular decompression (MVD)in , Afliated School from January 202O to December 2022 were colected. During surgery,17 patients were confirmed without vascular compression. se patients underwent trigeminal nerve sensory root combing. A retrospective analysis was conducted on the clinical characteristics, surgical efficacy,and complications this group. ResultsAmong 17 patients underwent sensory root combing,13 patients achieved clinical cure,3 experienced pain relief, and 1showed no improvement postoperatively.13 patients developed varying degrees facial numbness,with no other significant complications. average folow-up period was 46.2 months,during which 2 cases experienced pain recurrence.ConclusionsTrigeminal nerve combing is safe and eective for TN without vascular compression,and most patients may experience postoperative facial numbness.
Keywords: trigeminal neuralgis; microvasculardecompression; fending vessels;nerve combing
三叉神經痛(trigeminalneurolgia,TN)是常見的顱神經疾病,主要表現為患側三叉神經分布區域陣發性、反復發作的電擊樣或刀割樣劇烈疼痛[1]。根據其致病因素,可將其分為原發性和繼發性。對于繼發性TN,常由多發性硬化或神經受到諸如橋小腦角區腦膜瘤、表皮樣囊腫等顱內占位性病變壓迫所致。而原發性TN的病因目前尚未完全明確,一般認為,原發性TN是由于三叉神經腦池段受到血管壓迫引起[2-4]。然而,根據相關文獻報道及既往診療經驗,臨床上存在部分原發性TN患者,其三叉神經顱內段并無明確的血管壓迫[5-6]。南京大學醫學院附屬鼓樓醫院神經外科2020年1月—2022年12月共行顯微血管減壓術(microvasculardecompresssion,MVD)治療原發性TN患者共計455例,其中17例患者術中反復探查,確認無明確血管壓迫,予行神經梳理術,本文結合該組患者的臨床資料、術中所見及治療結果,探討無血管壓迫類型TN患者的病因、發病機制和治療策略。現報告如下。
1 資料與方法
1.1一般資料本組患者共計17例,其中男6例,女11例;年齡42\~75歲,平均年齡 (58.12±9.4) 歲;疼痛位于左側12例,右側5例;術前病程范圍為10個月 ~17 年,平均 (5.16±4.8) 年。所有患者術前均常規行顱神經核磁共振成像(magneticresonanceimaging,MRI)薄層平掃,排除繼發性因素,同時初步了解三叉神經與周圍血管關系、蛛網膜下腔寬度等,本組患者均排除嚴重心肺疾病等手術禁忌證。本研究經南京大學醫學院附屬鼓樓醫院倫理委員會審批通過(審批號: 2022-134-02) ,所有患者或家屬均簽署知情同意書。
1.2手術方法常規靜脈全麻,氣管插管后,患者取側臥位,固定頭部,采用患側乙狀竇后入路,耳后直線形切口約 6~8cm 。……