【中圖分類號】 R651;R739.41 【文獻標志碼】A 【文章編號】 1672-7770(2025)02-0201-04
Abstract: ObjectiveTo summarize the clinical effect full-neuroendoscopic trans-lateral supraorbital approach in the treatment sellar tumors.Methods clinical data 18 patients with sellar tumors admited to the the First People's Hospital from January 2O2O to June 2O23 were analyzed retrospectively.All patients underwent full-neuroendoscope to remove tumors through trans-lateral supraorbital approach,and were follwed up for 12 to 36 months after surgery,with follow-up head magnetic resonance imaging. Results Total resection was achieved in 15 cases(83. 3% )and subtotal resection in 3 cases(16. 7% ). Postoperative hypopituitarism occurred in 2 cases , transient diabetes insipidus and water-electrolyte disturbance in3 cases,frontal lobe contusion in1case and intracranial infectionin1 case.After 12 -36 months follow-up,there was no recurrence tumor and no progress residual tumor. ConclusionsIt is safe and efective to remove sellar tumors through trans-lateral supraorbital approach by full-neuroendoscope.
Key words: neuroendoscopy surgery; lateral supraorbital approach; microsurgery ; sellar tumor
鞍區位于顱底中央,位置深在,結構復雜,毗鄰重要血管神經,是神經外科手術難度最高區域之二[1]。傳統顯微外科開顱手術存在顯露不清、腦組織牽拉過多等諸多弊端[2],而近年來內鏡經鼻入路由于其避免腦組織牽拉、保護視神經和頸內動脈等重要結構的優勢,在鞍區腫瘤的手術治療中展現出獨特的作用與價值[3-5],然而,腦脊液鼻漏、顱內感染等問題亟待解決,且該入路對對偏側生長的腫瘤難以切除。神經內鏡經眶上外側入路相關技術[6]為鞍區腫瘤治療提供了全新的手術思路。本研究回顧性分析2020年1月—2023年6月常州市第一人民醫院神經外科收治的18例鞍區腫瘤患者,旨在探討全神經內鏡技術經眶上外側人路治療鞍區腫瘤的臨床療效。現報告如下。
1資料與方法
1.1一般資料共納入18 例鞍區腫瘤患者,其中男8例,女10例;年齡41\~76歲,平均年齡63歲;垂體瘤4例,顱咽管瘤7例(復發1例),腦膜瘤7例(鞍結節腦膜瘤5例,前床突腦膜瘤2例)。17例患者為首次手術治療。首發癥狀包括視力下降7例,視物重影2例,頭暈頭痛5例,嘔吐1例,肢體乏力2例,無癥狀(體檢發現)1例。術前檢查發現垂體功能低下者2例,余內分泌檢查均無異常。所有患者或家屬均簽署知情同意書。
1.2影像學檢查術前均進行鞍區計算機斷層掃描(computed tomography,CT)及三維重建,明確顱底骨質氣化、受侵及腫瘤鈣化情況,辨認重要顱底解剖結構。核磁共振成像(magneticresonanceimaging,MRI)平掃及增強明確腫瘤性質、大小、生長或侵襲方向,其中鞍上生長12例,突入第三腦室2例,突向偏側或兩側6例,瘤體直徑 2~5cm !……