微聚焦超聲聯合可注射型膠原蛋白在面部年輕化治療中的應用

[摘要]目的：評估微聚焦超聲與可注射型膠原蛋白聯合應用對面部年輕化改善的效果及安全性。方法：選取2021年9月-2023年6月在北京友誼醫院皮膚科門診就診的96例就醫者，隨機分為對照組（48例）和聯合組（48例），對照組僅使用微聚焦超聲治療，聯合組首先使用微聚焦超聲治療，在術后3個月時對就醫者淚溝處進行膠原蛋白注射。以微聚焦超聲術后為治療監測時間起點，收集兩組就醫者微聚焦超聲術后3個月、4個月及膠原蛋白注射術后1個月的照片，最終主要觀察指標為微聚焦超聲術后4個月與聯合應用膠原蛋白術后1個月兩組就醫者的臨床效果及滿意度。結果：聯合組總有效率為95.74%，總滿意度為93.62%，顯著高于對照組71.74%（P＜0.05），76.09%（P＜0.05）。結論：微聚焦超聲與可注射型膠原蛋白聯合應用對面部年輕化改善效果顯著，疼痛度低，并發癥少，就醫者的滿意度較高。

[關鍵詞]微聚焦超聲；膠原蛋白；面部年輕化；安全性；注射

[中圖分類號]R622" " [文獻標志碼]A" " [文章編號]1008-6455（2024）12-0124-04

Application of Micro-Focused Ultrasound Combined with Injectable Collagen in Facial Rejuvenation Treatment

BAO Tong， ZHENG Jiaxing， YANG Gaoyun， LI Linfeng

（ Department of Dermatology， Beijing Friendship Hospital， Capital Medical University， Beijing 100050， China ）

Abstract： Objective" To assess the efficacy and safety of the combined application of micro-focused ultrasound （MFU） and injectable collagen for facial rejuvenation. Methods" Ninety-six patients who visited the dermatology outpatient department at Beijing Friendship Hospital between September 2021 and June 2023 were randomly assigned to two groups： the control group （48 patients） and the combination treatment group （48 patients）. The control group received only MFU treatment， while the combination group underwent MFU treatment followed by a collagen injection in the tear trough area three months post-procedure. Photographs were taken at three and four months post-MFU treatment and one month post-collagen injection. The primary outcome measures were clinical efficacy and patient satisfaction at four months post-MFU and one month post-collagen injection. Results" The overall effective rate of the combination treatment group was 95.74%， and the overall satisfaction rate was 93.62%， significantly higher than those of the control group， which were 71.74%（P＜0.05）and 76.09%（P＜0.05）， respectively. Conclusion" The combination of micro-focused ultrasound and injectable collagen significantly improves facial rejuvenation outcomes， with minimal pain， fewer complications， and higher patient satisfaction.

Key words： micro-focused ultrasound; collagen; facial rejuvenation; safe; injection

面部的衰老問題是多層次、多部位老化的綜合原因形成的[1]，既往的抗衰治療方法主要有侵入性和非侵入性治療兩種，侵入性治療（如手術、線雕等）雖然效果較好，但創傷過大、恢復期較長等問題讓很多就醫者望而卻步。而非侵入性（如聚焦超聲、射頻[2]、鉺激光等）治療雖然創傷小，恢復期短，但在改善面部松弛下垂的治療中也存在效果維持時間短、疼痛等問題。因此對于面部衰老問題，單一的治療方案會存在一定的不足[3-4]，對于全面部的抗衰治療，需要在效果和舒適度方面做好平衡，以達到更好的就醫者滿意度。……