腹膜透析和血液透析對尿毒癥患者殘余腎功能及并發癥的影響分析

李藝蝦　楊楓

[摘要] 目的 探討尿毒癥患者采取腹膜透析和血液透析對殘余腎功能及并發癥影響。 方法 選取2018年1月至2019年12月福州市第一醫院腎內科收入尿毒癥患者190例，按照隨機數字表法分為兩組，每組各95例，對照組采用血液透析治療，觀察組采用腹膜透析治療，比較兩組干預前后腎功能及并發癥。 結果 治療前，兩組腎功能水平比較，差異無統計學意義（P>0.05），治療后，兩組腎功能水平比較，差異無統計學意義（P>0.05），兩組治療前后組內比較，差異有統計學意義（P<0.05）;治療前，兩組炎癥水平比較，差異無統計學意義（P>0.05），治療后，觀察組炎癥水平低于對照組，差異有統計學意義（P<0.05），兩組治療前后炎癥水平組內比較，差異有統計學意義（P<0.05）;觀察組并發癥率為6.32%，低于對照組的15.79%，差異有統計學意義（P<0.05）。 結論 血液透析與腹膜透析均是保護殘余腎功能有效透析模式，但腹膜透析降低炎癥指標水平更為顯著，且并發癥發生率偏低，可考慮作為尿毒癥患者首要透析方式。

[關鍵詞] 腹膜透析;血液透析;尿毒癥;腎功能;并發癥

[中圖分類號] R692.5? ? ? ? ? [文獻標識碼] B? ? ? ? ? [文章編號] 1673-9701（2021）19-0056-04

Analysis on the impacts of peritoneal dialysis and hemodialysis on residual renal function and complications in patients with uremia

LI Yixia? ?YANG Feng

Department of Nephrology，the First Hospital of Fuzhou，Fuzhou? ?350004，China

[Abstract] Objective To investigate the impacts of peritoneal dialysis and hemodialysis on residual renal function and complications in patients with uremia. Methods A total of 190 patients with uremia admitted to the department of nephrology of the First Hospital of Fuzhou from January 2018 to December 2019 were selected and divided into the control group（n=95） and the observation group（n=95） according to the random number table.The control group was given hemodialysis treatment，while the observation group was given peritoneal dialysis treatment.The renal function and complications before and after intervention were compared between the two groups. Results Before treatment，there was no statistically significant difference in renal function between the two groups（P>0.05）. After treatment，there was no statistically significant difference in renal function between the two groups（P>0.05）. However，there was statistically significant difference in each group before and after treatment（P<0.05）. Before treatment，there was no statistically significant difference in the level of inflammation between the two groups（P>0.05）. While after treatment，the level of inflammation in the observation group was lower than that in the control group，with statistically significant difference（P<0.05）. There was statistically significant difference in the level of inflammation in each group before and after treatment（P<0.05）. The complication rate in the observation group was 6.32%，which was lower than 15.79% in the control group，with statistically significant difference（P<0.05）. Conclusion Hemodialysis and peritoneal dialysis are both effective dialysis modes to protect residual renal function，but peritoneal dialysis can reduce the level of inflammation index more significantly，and the incidence of complications is relatively low，so it can be considered as the primary dialysis mode for patients with uremia.