苓桂術甘湯聯合溫膽湯治療痰濕壅盛型糖尿病的效果觀察

梁艷彬

[摘要] 目的 探究苓桂術甘湯聯合溫膽湯治療痰濕壅盛型糖尿病的臨床效果。方法 選擇2017年9月—2019年6月到該院就診的52例痰濕壅盛型2型糖尿病為研究對象，根據治療方案不同進行分組，對照組（n=26）采用常規西藥治療，觀察組（n=26）在常規西藥治療的基礎上應用苓桂術甘湯聯合溫膽湯治療，對比兩組血糖指標、中醫證候積分以及不良反應發生情況。結果 兩組干預前的空腹血糖、餐后2 h血糖、糖化血紅蛋白水平差異無統計學意義（P>0.05），觀察組患者干預后的上述血糖指標明顯低于對照組（P<0.05）。經治療后，觀察組患者在肥胖、口渴不欲飲、肢體困重倦怠、舌苔厚膩方面的中醫癥候積分顯著低于治療前及對照組（P<0.05）。兩組不良反應發生率比較，差異無統計學意義（P>0.05）。結論 苓桂術甘湯聯合溫膽湯治療痰濕壅盛型糖尿病效果顯著，可明顯緩解臨床癥狀，降低血糖，且其安全性較好。

[關鍵詞] 糖尿病;痰濕壅盛型;苓桂術甘湯;溫膽湯

[中圖分類號] R587 ? ? ? ? ?[文獻標識碼] A ? ? ? ? ?[文章編號] 1672-4062（2020）07（b）-0064-03

[Abstract] Objective To explore the clinical effect of Lingguishugan Decoction combined with Wendan Decoction in treating phlegm-dampness type diabetes. Methods A total of 52 patients with type 2 diabetes with phlegm， and dampness were selected as the research subjects from September 2017 to June 2019. The control group（n=26） was treated with conventional Western medicine and observation group（n=26） was treated with Lingguishugan decoction combined with Wendan decoction on the basis of conventional western medicine treatment， and the blood glucose index Tcm Sydromeinter and adverse reactions were compared between the two groups. Results There was no statistically significant difference in fasting blood glucose， blood glucose 2h after meals， and glycated hemoglobin levels before intervention between the two groups（P>0.05）. The above-mentioned blood glucose indexes of observation group after intervention were significantly lower than those of control group （P<0.05）. After treatment， the observation group's TCM symptom scores for obesity， thirst， unwillingness to drink， limbs tiredness， thick tongue coating was significantly lower than before treatment and control group（P<0.05）. The incidence of adverse reactions between the two groups was not statistically significant difference（P>0.05）. Conclusion Lingguishugan decoction combined with Wendan decoction is effective in treating phlegm-dampness type diabetes. It can obviously relieve clinical symptoms and lower blood glucose， and its safety is good.

[Key words] Diabetes; Phlegm-dampness type; Lingguishugan Decoction; Wendan Decoction

2型糖尿病是以慢性血糖水平升高為主要特征的代謝性疾病，其發生主要是由于機體胰島素作用缺陷或分泌不足而引起的。近年，隨著人們生活方式以及膳食結構的不斷改變，該病發生率逐年升高，成為繼心腦血管疾病、惡性腫瘤后第三大嚴重威脅人類身心健康的慢性非傳染性疾病。當前臨床往往予以常規西藥進行治療，以使患者的血糖水平控制到正常范圍，降低急慢性糖尿病并發癥發生風險，改善患者的生存質量。然而，單純應用西藥降糖，雖可在短時間內獲得滿意的療效，但長時間用藥有可能引起耐藥性，再加上大多數糖尿病患者為老年人，長期用藥不良反應發生風險高，故遠期療效并不理想[1]。現為探究中醫藥治療2型糖尿病的有效性及安全性，該研究選取2017年9月—2019年6月收治的52例痰濕壅盛型2型糖尿病患者，根據中醫辨證論治原則對痰濕壅盛型患者予以苓桂術甘湯和溫膽湯治療，具體報道如下。