針灸調(diào)控腸道菌群的研究進(jìn)展與思考

劉霞　胡舒寧　劉密　常小榮

摘要?腸道菌群作為人體龐大的微生態(tài)系統(tǒng)，與許多疾病的發(fā)生發(fā)展密切相關(guān)。針灸是治療疾病的重要方法之一，對腸道菌群的調(diào)節(jié)作用也越來越受到關(guān)注。臨床及動物實(shí)驗(yàn)都已證實(shí)針灸治療可以調(diào)節(jié)腸道菌群趨于平衡。該文整理了近年來腸道菌群研究方法的發(fā)展、針灸對胃腸道疾病和代謝性疾病的腸道菌群調(diào)控作用，并對針灸干預(yù)腸道菌群研究中的問題和發(fā)展方向進(jìn)行了一定的展望。

關(guān)鍵詞?針灸;腸道菌群;胃腸道疾病;代謝性疾病;調(diào)控;進(jìn)展

Research Advances and Thoughts of Acupuncture in Regulating Intestinal Flora

Liu Xia1，Hu Shuning1，Liu Mi1，2，Chang Xiaorong1

（1 College of Acupuncture-Moxibustion and Tuina，Hunan University of Chinese Medicine，Changsha 410208，China; 2 Liuyang Hospital of Chinese Medicine，Liuyang 410300，China）

Abstract?As a huge micro-ecological system of the human body，intestinal flora is closely related to the occurrence and development of many diseases. Acupuncture and moxibustion are important methods to treat diseases，and their regulation of intestinal flora has attracted more and more attention. Clinical and animal experiments have confirmed that acupuncture treatment can regulate the intestinal flora to become balanced. This paper compiled the development of research methods on intestinal flora in recent years as well as the influence of acupuncture on gastrointestinal diseases and metabolic diseases，and looked ahead to the problems and development direction of the research of acupuncture intervention in intestinal flora.

Key Words?Acupuncture and moxibustion; Intestinal flora; Gastrointestinal diseases; Metabolic diseases; Regulate; Advance

中圖分類號：R245文獻(xiàn)標(biāo)識碼：Adoi：10.3969/j.issn.1673-7202.2019.03.003

腸道菌群對人類健康的影響十分重要，逐漸成為研究的熱點(diǎn)和重點(diǎn)。作為人體內(nèi)最復(fù)雜和種群數(shù)量最高的微生態(tài)系統(tǒng)，腸道菌群被認(rèn)為是人體的一個被忽視的器官。人體腸道中定植的細(xì)菌的數(shù)量約為1×1014個，數(shù)量巨大的微生物是人體總細(xì)胞數(shù)的10倍。正常情況下，腸道菌群處于動態(tài)平衡的狀態(tài)，當(dāng)受到環(huán)境、藥物、毒素等因素的影響時，容易導(dǎo)致腸道菌群失調(diào)從而影響人類的健康。腸道菌群失衡容易引起胃腸道疾病、代謝性疾病、心腦血管疾病等，因此，對腸道菌群的調(diào)控作用成為研究的熱點(diǎn)，被認(rèn)為是治療相關(guān)疾病的潛在重要靶標(biāo)[1]。

針灸是針法和灸法的總稱，是指在中醫(yī)理論的指導(dǎo)下，選用不同的針法或灸法對人體的穴位施予一定的刺激，達(dá)到激發(fā)機(jī)體自身內(nèi)在的調(diào)整能力，實(shí)現(xiàn)陰陽平衡，恢復(fù)機(jī)體穩(wěn)態(tài)，以達(dá)到防治疾病的目的。……