99TcmO-4甲狀腺顯像聯合Tg/TSH對分化型甲狀腺癌術后殘甲的評估價值

劉學，韋智曉，李俊紅，周世亮，李藹峰，彭盛梅，張筱楠，田甜

(1廣西醫科大學第一附屬醫院，南寧530000；2懷化市第一人民醫院)

99TcmO-4甲狀腺顯像聯合Tg/TSH對分化型甲狀腺癌術后殘甲的評估價值

劉學1，2，韋智曉1，李俊紅1，周世亮2，李藹峰1，彭盛梅1，張筱楠1，田甜1

(1廣西醫科大學第一附屬醫院，南寧530000；2懷化市第一人民醫院)

甲狀腺腫瘤，分化型；甲狀腺核素掃描；甲狀腺球蛋白；促甲狀腺激素

1 資料與方法

1.1 臨床資料 選擇2014年1月～2015年11月廣西醫科大學第一附屬醫院收治的DTC患者302例，男84例、女218例，年齡18～79(40.65±13.73)歲。均行甲狀腺全切或次全切除術，經病理檢查證實為甲狀腺乳頭狀癌或濾泡狀癌；均首次接受清甲治療，且符合清甲治療標準[1，2]。排除有遠處轉移或甲狀腺球蛋白抗體(TgAb)陽性者。術后3～4周均接受131I清甲治療，單次131I為2 960～4 810 MBq口服，住院觀察5～7 d。

1.2 血清TSH、Tg、TgAb檢測 患者甲狀腺顯像前1 d早晨空腹采集肘正中靜脈血3 mL，3 000 r/min離心3～5 min，提取血清，密閉保存于-20 ℃冰箱中備用。采用化學發光法(美國貝克曼DXI 800型全自動化學發光儀)檢測血清TSH、Tg、TgAb。試劑盒由貝克曼公司提供。

2 結果

3 討論

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[14] 張英杰,林巖松,梁軍.甲狀腺癌失分化機制的研究進展[J].中華核醫學與分子影像雜志,2014,34(4):327-330.

廣西壯族自治區科學技術廳科技攻關與新產品試制項目(桂科攻0861003);廣西壯族自治區科學技術廳基礎性研究項目(桂科基0779027)。

韋智曉(E-mail:weizhixiao196493@126.com)

10.3969/j.issn.1002-266X.2017.05.022

R736.1

B

1002-266X(2017)05-0067-03

2016-09-05)