硼、硅有機化合物的特性和應用研究進展報告

席振峰+張文雄+王劍波+謝作偉+王從洋

摘要：有機硼、硅在合成化學、醫藥產業以及材料科學中有重要用途，對有機硼、硅元素化學的研究具有重大的戰略意義。在硼有機化合物的特性和應用研究方面，我們取得了下面的重要進展：1.發展了制備有機硼化物的新方法；2.結合機理研究，發展了一種方便且高效的合成偕二硼化合物的新方法；3.研究了原位生成的鋯-碳硼炔配合物與烯烴的反應性，高收率和高選擇性地合成了一系列碳硼烷鋯雜環戊烷配合物；4.發展了一個通過三組分[2+2+2]環加成策略高效合成多取代苯并碳硼烷化合物的新方法；5.研究了原位生成的碳硼炔與烷基芳烴的反應性；6.得到了合成一系列官能團化二茂鐵基碳硼烷化合物的便利方法。 在硅有機化合物的特性和應用研究方面，我們取得了下面的重要進展：1.開展了過渡金屬催化的硅-碳鍵的選擇性活化和重組研究；2.首次實現了過渡金屬催化的三甲基硅中碳-氫鍵的催化活化；3.從烯基硅出發，經過分子內Mizoroki-Heck反應，合成了一系列具有重要用途的含硅雜環化合物。 在此基礎上，形成我國硼、硅有機化合物研究的特色研究，同時提升我國硼、硅有機化學在國際上的影響力和競爭力。

關鍵詞：有機硅；有機硼；碳硼烷；硅雜環

Study on Properties and Applications of Organoboron and Organosilicon Compounds

Abstract：Organoboron and Organosilicon compounds， which are widely used in synthetic chemistry， materials and pharmaceutical industry， are of strategic significance in boron and silicon element chemistry. In the research of properties and applications of organoboron compounds， we have made great progress as follows： 1. A new method for preparing organic boride has been developed. 2. By mechanism study， a convenient and efficient synthesis method of gem-boron compounds has been developed. 3. Zirconium-1，2-dehydro-o-carborane complexes generated in situ have been studied and the high yield and high selective synthesis of a series of carborane zirconacyclopentene complexes has been achieved. 4. Through a three-component [2+2+2] cycloaddition strategy， an efficient method to synthesize multi-substituted benzocarborane compounds has been developed. 5. The reaction of 1，2-dehydro-o-carborane complexes generated in situ with alkyl aromatics has been studied. 6. A series of functionalized ferrocenyl carborane compounds have been synthesized in a convenient way. In the research of properties and applications of organosilicon compounds， we have made great progress as follows： 1. Transition metal catalyzed silicon-carbon bond selective activation and reorganization have been studied. 2. The transition metal catalyzed silicon-based carbon-hydrogen activation has been achieved for the first time. 3. A series of important silicon-containing heterocyclic compounds have been synthesized through intramolecular Mizoroki-Heck reaction starting from alkenyl silicon compounds. On this basis， we have formed our own organoboron and organosilicon chemistry system and improve our influence and competitiveness in boron and silicon chemistry in the world.

Keywords：Organosilicon；Organoboron；Carborane；Silole

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