王鵬飛
[摘要] 目的 探討肝硬化門脈高壓癥繼發脾功能亢進、胃底靜脈曲張患者行手助腹腔鏡與開腹賁門周圍血管離斷、脾臟切除術的肝功能變化及臨床療效。方法 回顧性分析2010年1月—2013年1月施行脾臟切除、賁門周圍血管離斷術治療肝硬化門靜脈高壓癥72例,其中手助腹腔鏡手術組29例、開腹手術43例。術前按Child法進行肝功能分級,對比分析兩組手術時間、術中失血量、術后并發癥發生率、肝功能損害和死亡率。 結果 手助腹腔鏡組與開腹組術中并發癥發生率差異無統計學意義(P>0.05);開腹組ALT、AST術后均比術前顯著升高,差異均有統計學意義(P<0.05),手助腹腔鏡組ALT、AST術后均較術前升高,其中AST升高有統計學意義(P<0.05)。結論 手助腹腔鏡脾臟切除加賁門周圍血管離斷術對肝功能影響較開腹組小,術后并發癥少,是相對安全可行的。
[關鍵詞] 手助腹腔鏡; 脾切除術;賁門周圍血管離斷術;門脈高壓
[中圖分類號] R4 [文獻標識碼] A [文章編號] 1674-0742(2015)09(a)-0111-03
Clinical Comparative Analysis of Hand-assisted Laparoscopic Versus Open
Splenectomy Combined with Extensive Devascularization Rround the Cardia
WANG Peng-fei
Department of Surgery, Third People's Hospital of Xinyang. Xinyang, Henan Province, 464000 China
[Abstract] Objective To discuss the change of liver function in the patients after hand-assisted laparoscopic or open splenectomy combined with extensive devascularization around the cardia for treating secondary hypersplenism gastric varices due to cirrhotic portal hypertension and the treatment effect. Methods Retrospective analysis on 72 patients with cirrhotic portal hypertension who underwent splenectomy combined with extensive devascularization around the cardia in our hospital between January 2010 and January 2013 was carried out. There were 29 patients in the hand-assisted laparoscopic group and 43 in the open group. Child-pugh classification of liver function was undertaken preoperatively, and the operation duration, intraoperative blood loss, postoperative complication rate and mortality was comparative analyzed between the two groups. Results There was no statistically significant difference between the two groups in intraoperative complications, P>0.05; ALT and AST were higher after treatment than before in the open group, and the differences were statistically
隨著腹腔鏡手術的成熟和新器械的使用,以微創手術處理門靜脈高壓癥成為可能。但肝硬化門靜脈高壓癥患者側支循環豐富,且凝血機制差,故腹腔鏡下行賁門周圍血管離斷、脾臟切除術具有很大難度。近年來國內對門靜脈高壓癥行手助腹腔鏡脾臟切除加斷流術的報道日漸增多[1],可降低復雜腹腔鏡手術的難度和風險,手助腹腔鏡手術(hand-assisted laparoscopic surgery,HALS)已成為近年興起的一種新型腹腔鏡手術方式。該研究回顧分析該院2010年1月—2013年1月期間進行的開腹手術43例與手助腹腔鏡下脾臟切除加斷流術29例進行了臨床對比分析,現報道如下。
1 資料與方法
1.1 一般資料
回顧分析該院2010年1月—2013年1月因肝硬化門脈高壓癥并發食管胃底靜脈曲張、脾功能亢進等行脾切除加斷流術的72例臨床資料:其中手助腹腔鏡29例,開腹43例。手助……