Mantle Cell Lymphoma in a Lacrimal Gland in a Female and a Review of the Literature

Jianhao Cai， Zeyi Li， Yuansheng Zhou

Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong，Shantou 515041， China．

Introduction

Case report

Figure 1 The appearance of the patient．Right supraorbital swelling with round lymphadenopathy in the lacrimal gland regions．

Figure 2 Computerized tomography （CT） scan．Mass in bilateral lacrimal gland region， more significant in right eye（a．horizontal position， b．coronal position）

Figure 3 The general appearance of lacrimal gland mass．a．The mass located in the lacrimal gland fossa．b．The mass conformed to the shape of the globe with black-violet color，soft texture，and measured about 24 mm×26 mm×6 mm．

Discussion

Figure 4 histological examination of the mass．HE stain shows that infiltration by monomorphic cell population composed of small-to medium-sized lymphocytes with irregular， indented， or cleaved nuclei， condensed chromatin， and scant cytoplasm．The growth pattern was diffuse and partially nodular （a，200×）．Immunohistochemical study revealed that tumor cells were CyclinD1（b）， CD5（c）， CD20（d）， CD79a（e）， and Pax-5（f） positive（400×）．

Acknowledgement