Image Features of Retinal Astrocytic Hamartoma in a Patient with Tuberous Sclerosis Complex

Peng Zhang， Dongjie Sun， Jinting Zhu， Juan Li， Yusheng Wang

Department of Ophthalmology， Fourth Military Medical University， Eye Institute of Chinese PLA， Xi′an 710032，China

Introduction

Case presentation

Figure 1 Facial angiofibromas in a butterfly distribution around the patient's nose and chin

Figure 2 Well-circumscribed， rough， elevated， and coffeecolored shagreen patches on the skin of the patient's back．

Figure 3 Fundus photography of the right eye showed a retinal astrocytic hamartoma bordering on the optic disk and presenting as a well-circumscribed，mulberry-like lesion consisting of glistening yellowish spherules of calcification．

Figure 4 Fundus autofluorescence of the right eye demonstrated the well-circumscribed mass composed of multiple intensely hyper-autofluorescence spots corresponding to the glistening yellowish spherules of calcification in the retinal astrocytic hamartoma．

Figure 5 Fundus fluorescein angiography of the right eye revealed fluorescein leakage from dilated retinal capillaries over the retinal astrocytic hamartoma．

Figure 6 Spectral domain optical coherence tomography showed moth-eaten optically empty spaces， hyperreflective dots within retinal astrocytic hamartoma，and the uneven surface of the lesion．

Discussion