【摘 要】 目的 分析復方甘草酸苷及異甘草酸鎂治療酒精性肝炎的臨床療效。方法 按照抽簽法將我院2013年1月-2013年11月收治的50例酒精性肝炎患者分為治療組(25例)和對照組(25例),分別給予異甘草酸鎂和復方甘草酸苷治療,對比兩組患者臨床療效。結果 治療組總有效率為96%,對照組總有效率為68%,治療組總有效率明顯高于對照組,(P<0.05)。治療組血ALT、AST、TBIL改善情況明顯優于對照組(P<0.05),治療組無明顯不良反應,對照組出現3例雙下肢浮腫,停藥后自愈。結論 異甘草酸酶治療酒精性肝炎的臨床療效高于復方甘草酸苷治療效果,可明顯改善肝功能,療效顯著,值得肯定。
【關鍵詞】 復方甘草酸苷;異甘草酸鎂;酒精性肝炎
【中圖分類號】 R575.1 【文獻標識碼】 B
Clinical analysis of glycyrrhizin and MgIG treatment of alcoholic hepatitis
Zhou Liying
(Shangqiu City,Henan Province Branch of the First People's Hospital Infection Ward,Shangqiu,476100)
【Abstract】 Objective To analyze the clinical efficacy of glycyrrhizin and MgIG treatment of alcoholic hepatitis. Methods According to the draw method to our hospital in January 2013-2013 in November treated 50 patients with alcoholic hepatitis patients were divided into treatment group (25 cases) and control group (25 cases) were given MgIG and glycyrrhizin treatment, compared two groups of patients in clinical efficacy. Results The total effective rate was 96 % in the control group, the total effective rate was 68%, the total efficiency of the treatment group was significantly higher, (P<0.05). Treated blood ALT, AST, TBIL improvement than the control group (P <0.05),the treatment group had no significant adverse reactions, the control group had three cases of lower extremity edema, after stopping to heal. Conclusion The clinical efficacy isoglycyrrhizinate enzyme treatment of alcoholic hepatitis is higher than glycyrrhizin treatment can significantly improve liver function, a significant effect, worthy of recognition.
【Keywords】 glycyrrhizin;MgIG;alcoholic hepatitis
酒精性肝炎是在長期過量飲酒導致的肝臟疾病,主要表現為惡心嘔吐、黃疸、肝臟腫大等,后期可能誘發肝功能衰竭和上消化道出血,嚴重危害了患者身體健康和生命安全。在此次研究中,筆者以50例酒精性肝炎患者作為此次研究對象,分別給予異甘草酸鎂和復方甘草酸苷治療,分析其治療效果,現總結如下。
1 資料與方法
1.1 一般資料 我院2013年1月-2013年11月收治的50例酒精性肝炎患者,經診斷,與中華醫學會制定的酒精性肝炎診斷標準相符[1]。男35例,女15例;年齡25-72歲,平均年齡(45.5±3.8)歲;病程1-15年,平均病程(5.4±1.4)年;患者均出現腹脹、食欲不振、腹瀉、腹痛、惡心嘔吐,部分患者出現而黃疸、發熱及壓痛等癥狀;按照抽簽法分為治療組(25例)和對照組(25例),兩組患者年齡、性別、病程及臨床癥狀等對比,差異無統計學意義,可進行比較(P>0.05)。……