惡性腫瘤患者化療期的心電圖變化探究

【摘 要】 目的分析探討惡性腫瘤患者化療期間心電圖變化。方法選取我院近年來收治的100例惡性腫瘤化療患者作為研究對象，觀察比較化療3天、化療一周、化療一個月三個時點(diǎn)惡性腫瘤患者化療期間心電圖變化，總結(jié)惡性腫瘤患者化療對其心電圖影響。結(jié)果本組患者化療第三天心電圖異常發(fā)生率高達(dá)80.0%，化療一周心電圖異常發(fā)生率為65.0%，化療一個月后心電圖異常發(fā)生率為49.0%，化療第三天、化療一周、化療一個月患者心電圖異常發(fā)生率比較存在顯著差異（P＜0.05）。60歲以上患者心電圖異常發(fā)生率明顯高于其它年齡段患者（P＜0.05）。含蒽環(huán)類化療方案治療患者R波低電壓、T波低平、ST段下降發(fā)生率明顯高于不含蒽環(huán)類化療方案治療患者（P＜0.05）。結(jié)論惡性腫瘤患者化療期間會伴有顯著的心電圖變化，需要基于惡性腫瘤化療期間患者心電圖變化特點(diǎn)著重加強(qiáng)心功能動態(tài)監(jiān)測，以及時糾正患者機(jī)體狀態(tài)，改善化療預(yù)后效果，保證患者生命安全。

【關(guān)鍵詞】 惡性腫瘤；化療；心電圖；異常

【中圖分類號】 R730.5【文獻(xiàn)標(biāo)識碼】 BExplore the ECG changes of m alignant tumor patients during chemotherapy

Li Yu

(Hunan Provincial Tumor Hospital of Hunan Changsha，410000)【Abstract】 ObjectiveTo investigate the ECG changes during cancer chemotherapy patients. MethodsIn recent years， the hospital admitted 100 cases of cancer chemotherapy patients as research subjects， observation and comparison of chemotherapy three days， a week of chemotherapy， chemotherapy month three time points during chemotherapy in patients with m alignant ECG changes， summarize their cancer chemotherapy patients ECG affected. ResultsThe third day of chemotherapy incidence of ECG abnormalities up 80.0%， 65.0% in the chemotherapy week was abnormal ECG， ECG abnormalities occurred one month after chemotherapy was 49.0%， the third day of chemotherapy， chemotherapy a week， a month of chemotherapy incidence of ECG abnormalities in patients with significant differences (P <0.05). ECG abnormalities in patients over the age of 60 were significantly higher than in patients with other age groups (P <0.05). Anthracycline-containing chemotherapy regimen in patients with low-voltage R wave， T wave flattening， ST segment depression were significantly higher than anthracycline-free chemotherapy treated patients (P <0.05). ConclusionPatients with cancer during chemotherapy will be accompanied by significant changes in ECG， ECG changes needed based on the characteristics of patients during cancer chemotherapy focused on strengthening the dynamic monitoring of cardiac function， as well as the state of the body when the patient to correct and improve the prognosis of chemotherapy to ensure the safety of patients.

【Keywords】 cancer;chemotherapy;electrocardiogram;abnormal臨床上常規(guī)心電圖檢查中，惡性腫瘤患者多伴有心電圖指標(biāo)異常，化療過程中心電圖指標(biāo)異常會出現(xiàn)一定程度的加重[1]。但是，原發(fā)性腫瘤患者臨床檢查時發(fā)現(xiàn)患者本身并無器質(zhì)性心臟病、糖尿病、高血壓病史，這便說明了腫瘤患者發(fā)生心電圖指標(biāo)異常多與腫瘤病變及其治療有直接關(guān)系[2]。為進(jìn)一步探討腫瘤患者心電圖異常特征，總結(jié)腫瘤患者心電圖異常改變的臨床意義，本文選取我院收治的100例惡性腫瘤患者作為研究對象，就其臨床資料進(jìn)行了回顧性分析，著重分析總結(jié)了惡性腫瘤患者化療期間心電圖變化，具體分析如下。……